santa cruz biotechnology, inc.
SCBT Logo

Welcome!        Items in Cart     Quick Order
home » Signaling Intermediates » IFIT Antibody / IFIT Antibodies » IFITM3 (F-41): sc-100768

IFITM3 (F-41) Antibody: sc-100768

  |  Datasheet
  • mouse monoclonal IgG1, 100 µg/ml
  • raised against recombinant IFITM3 of human origin
  • recommended for detection of IFITM3 of human origin by WB, IP and ELISA
 
Additional IFIT Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human IFITM3 10410 11p15.5 NM_021034 Q01628
 605579
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
IFITM3 (F-41) sc-100768 100 µg/ml $295
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
IFITM3 siRNA (h) sc-97053 10 µM $258
IFITM3 (h)-PR sc-97053-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
IFITM3 shRNA Plasmid (h) sc-97053-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
IFITM3 shRNA (h) Lentiviral Particles sc-97053-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
IFITM3 (h): 293T Lysate sc-110589 100µg/200µl $205

IFITM3 Background Information
IFITM3 (interferon induced transmembrane protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein that belongs to the IFITM (interferon inducible transmembrane) family of proteins. IFITM proteins are induced by type I and type II interferons and contain multiple interferon (IFN)-stimulated response elements (ISREs) in their promoter regions. IFITM proteins play important roles in many cellular processes and their expression requires the presence of the chromatin remodeling SWI/SNF-like BAF complexes. Cellular processes involving IFITM proteins include cellular anti-proliferative activities and homotypic cell adhesion functions of interferons. In addition, IFITM genes are often upregulated in various cancer cells, suggesting a possible role in carcinogenesis. Localizing to the membrane, IFITM3 is a 133 amino acid protein that is induced by IFN-å and IFN-©. IFITM3 expression can be regulated by TEF-1, Brg-1 and Sp1.
IFITM3 (F-41)
Click on image to enlarge
sc-100768
IFITM3 (F-41): sc-100768. Western blot analysis of IFITM3 expression in non-transfected: sc-117752 (A) and human IFITM3 transfected: sc-110589 (B) 293T whole cell lysates.
Download
Datasheets
Get Adobe Acrobat Reader