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home » Signaling Intermediates » Act1 Antibody / Act1 Antibodies » Act1 (WW-18): sc-100647

Act1 (WW-18) Antibody: sc-100647

  |  Datasheet
  • mouse monoclonal IgG2a, 100 µg/ml
  • raised against recombinant Act1 of human origin
  • recommended for detection of Act1 of mouse and human origin by WB, IP, IF, IHC(P) and ELISA
 
Additional Act1 Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human TRAF3IP2 10758 6q21 NM_147200, NM_147686 O43734
 607043
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Act1 (WW-18) sc-100647 100 µg/ml $295
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Act1 siRNA (h) sc-29634 10 µM $258
Act1 siRNA (m) sc-29635 10 µM $258
Act1 (h)-PR sc-29634-PR 10 µM $23
Act1 (m)-PR sc-29635-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Act1 shRNA Plasmid (h) sc-29634-SH 20 µg $520
Act1 shRNA Plasmid (m) sc-29635-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Act1 shRNA (h) Lentiviral Particles sc-29634-V 200 µl $625
Act1 shRNA (m) Lentiviral Particles sc-29635-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa nuclear extract sc-2120 1000 µg $143
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104

Act1 Background Information
Members of the NF˚B family of transcription factors are important in regulating the expression of various cellular and viral genes involved in immune and inflammatory responses, cell survival and stress responses. IL-1, TNFå and other related signaling pathways activate transcription factors through the activation of JNK. The NF˚B signaling pathway converges with the signal-induced activation of JNK upstream of IKK. Isolated from the human embryonic kidney (HEK) 293 cell line, Act1 is an IKK©-associated protein that activates both NF˚B and JNK constitutively. Act1, also designated NF˚B activator 1 or CIKS (for connection to IKK and SAPK/JNK), may function as a coordinator between two stress-induced signaling pathways.
Act1 (WW-18)
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sc-100647
Act1 (WW-18): sc-100647. Western blot analysis of Act1 expression in HeLa nuclear extract.
sc-100647
Act1 (WW-18): sc-100647. Immunofluorescence staining of paraformaldehyde-fixed HeLa cells showing nuclear and cytoplasmic localization.
sc-100647
Act1 (WW-18): sc-100647. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human small Intestine tissue showing membrane and cytoplasmic localization.
sc-100647
Act1 (WW-18): sc-100647. Western blot analysis of Act1 expression in Hep G2 nuclear extract.
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