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home » Synthesis and Degradation » LASS Antibody / LASS Antibodies » LASS4 (22.4): sc-100555

LASS4 (22.4) Antibody: sc-100555

  |  Datasheet
  • mouse monoclonal IgG2a, 100 µg/ml
  • raised against recombinant LASS4 of human origin
  • recommended for detection of LASS4 of mouse, rat and human origin by WB, IP and ELISA
 
Additional LASS Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human LASS4 79603 19p13.2 NM_024552 Q9HA82
 n/a
Mouse Lass4 67260 8 A1.1 Q9D6J1
 N/A
Mouse Lass4 67260 8 A1.1 Q9D6J1
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
LASS4 (22.4) sc-100555 100 µg/ml $295
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
LASS4 siRNA (h) sc-62549 10 µM $258
LASS4 siRNA (m) sc-62550 10 µM $258
LASS4 (h)-PR sc-62549-PR 10 µM $23
LASS4 (m)-PR sc-62550-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
LASS4 shRNA Plasmid (h) sc-62549-SH 20 µg $520
LASS4 shRNA Plasmid (m) sc-62550-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
LASS4 shRNA (h) Lentiviral Particles sc-62549-V 200 µl $625
LASS4 shRNA (m) Lentiviral Particles sc-62550-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104

LASS4 Background Information
The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis.
LASS4 (22.4)
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sc-100555
LASS4 (22.4): sc-100555. Western blot analysis of LASS4 expression in HeLa whole cell lysate.
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