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home » Kinases and Phosphatases » NDR Antibody / NDR Antibodies » NDR1 (YJ-7): sc-100404

NDR1 (YJ-7) Antibody: sc-100404

  |  Datasheet
  • mouse monoclonal IgG2a, 50 µg/0.5 ml
  • raised against recombinant NDR1 of human origin
  • recommended for detection of NDR1 of human origin by WB, IP, IF, IHC(P) and ELISA
 
Additional NDR Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human STK38 11329 6p21.31 NM_007271 Q15208
 606964
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
NDR1 (YJ-7) sc-100404 50 µg/0.5 ml $295
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NDR1 siRNA (h) sc-44366 10 µM $258
NDR1 (h)-PR sc-44366-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NDR1 shRNA Plasmid (h) sc-44366-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NDR1 shRNA (h) Lentiviral Particles sc-44366-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa nuclear extract sc-2120 1000 µg $143
Jurkat nuclear extract sc-2132 1000 µg $143
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104

NDR1 Background Information
The nuclear Dbf2-related kinases (NDR1 and NDR2) participate in the regulation of cell division and morphology and may be implicated in tumor progression. NDR1 and NDR2 share 86% amino acid identity, but differ in their expression pattern. NDR1 localizes to the nucleus, while NDR2 exhibits punctate cytoplasmic distribution. Also, NDR1 expression appears highest in spleen, lung and thymus, whereas NDR2 shows highest expression in the gastrointestinal tract. However, both NDR1 and NDR2 are regulated by phosphorylation and by the Ca2+-binding protein S-100B. NDR1 and NDR2 may also play a role in the HIV-1 life cycle. Both proteins are cleaved by the HIV-1 protease (PR), which inhibits their enzymatic activity and alters the subcellular localization of NDR2. The genes encoding human NDR1 and NDR2 map to chromosomes 6p21 and 12p11.23, respectively.

NDR1 (YJ-7)
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sc-100404
NDR1 (YJ-7): sc-100404. Western blot analysis of NDR1 expression in HeLa nuclear extract.
sc-100404
NDR1 (YJ-7): sc-100404. Immunofluorescence staining of paraformaldehyde-fixed HeLa cells showing nuclear localization.
sc-100404
NDR1 (YJ-7): sc-100404. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human malignant lymphoma, diffuse large B-cell tissue showing nuclear and cytoplasmic localization.
sc-100404
NDR1 (YJ-7): sc-100404. Western blot analysis of NDR1 expression in Jurkat nuclear extract.
sc-100404
NDR1 (YJ-7): sc-100404. Western blot analysis of NDR1 expression in PC-12 (A) and RAW 264.7 (B) whole cell lysates.
sc-100404
NDR1 (YJ-7): sc-100404. Western blot analysis of NDR1 expression in U-937 (A) and HEL 92.1.7 (B) nuclear extracts and human PBL whole cell lysate (C).
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