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- mouse monoclonal IgG2b, 100 µg/ml
- raised against recombinant ACP2 of human origin
- recommended for detection of ACP2 of human origin by WB, IP, IF, IHC(P) and ELISA
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Ordering Information
Recommended Support Products:
(click button of application of choice)
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
ACP2 |
53 |
11p11.2 |
NM_001610 |
P11117
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171650 |
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ACP2 Background Information
ACP2 (acid phosphatase 2), also known as LAP (lysosomal acid phosphatase), is a 423 amino acid member of the histidine acid phosphatase family. Localized to the lysosomal compartment, ACP2 is comprised of two subunits, designated alpha and beta, which function to hydrolyze orthophosphoric monoesters to alcohols and phosphates. ACP2 is expressed throughout the body and exerts optimal enzymatic activity when the lysosome is at an acidic pH. Defects in the gene encoding ACP2 are the cause of acid phosphatase deficiency, a condition characterized by terminal bleeding, opisthotonos, hypotonia, lethargy, intermittent vomiting and death in early infancy.
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ACP2 (4B5)
Click on image to enlarge
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ACP2 (4B5): sc-100344. Immunofluorescence staining of paraformaldehyde-fixed HeLa cells showing cytoplasmic localization.
ACP2 (4B5): sc-100344. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human lymphoma tissue showing cytoplasmic localization.
ACP2 (4B5): sc-100344. Western blot analysis of ACP2 expression in HeLa whole cell lysate.
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