Welcome to Santa Cruz Biotechnology!

Transcription Factor Activators

Introducing HOVERcruz™,

a unique system for rapid identification of chemicals of interest. Hover over product names in the table to see representative images for each product.

Live chat is now available! (click here)

Our live chat system is available to answer your product and ordering questions.

PRODUCT NAMECATALOG #DESCRIPTIONCITATIONSRANKING
1,4-DPCAsc-200758A potent and selective inhibitor of prolyl 4-hydroxylation both in vitro (IC50=2.4-4.5 mM) and in vivo. CAS # 331830-20-7

1
CP 31398 dihydrochloridesc-205270CP 31398 dihydrochloride has been shown to act as a stabilizing agent for p53, and to promotes activity of p53 in cancer cell lines. CAS # 259199-65-0

Amifostinesc-200937A broad-spectrum radio- and chemoprotector. Restores transcriptional activity of specific p53 mutants, prevents chemotherapy-induced apoptosis, upregulates HIF-1α and can act as a free radical scavenger. CAS # 20537-88-6

3
BTZO 1sc-362720BTZO 1 is a suppressor of cardiomyocyte apoptosis presumably by activation of antioxidant response element (ARE)-mediated gene expression. CAS # 99420-15-2

Dimethyloxaloylglycine (DMOG) sc-200755Dimethyloxaloylglycine (DMOG) is an inhibitor of PHF (prolyl hydroxylase, PHD) and asparaginyl hydroxylase FIH-1 (Factor inhibiting HIF, FIH). CAS # 89464-63-1

3
PRIMA-1sc-200927PRIMA-1 is a reactivator of deficient p53. Induces p53-dependent apoptosis in mutant-type p53 and p53-deficient systems. CAS # 5608-24-2