Stem Cell Reagents

• AICAR
  Strongly inhibits the transcription of PPARα, the coactivation of PPARα, and adipocyte differentiation. Can activate AMPK and mimic insulin activity.

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-200659	2627-69-2	C9H14N4O5	50 mg/250 mg

• Caged Retinoic Acid
  Photoactivatable form of retinoic acid.

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-202089	1040124-47-7	C29H37NO6	500 µg

• Cardiogenol C
  A cell-permeable pyrimidine compound which potently induces the differentiation of ESCs (embryonic stem cells) into cardiomyocytes (EC₅₀= 100 nM) without significant cytotoxic effect, even at concentrations as high as 25 µM. The induction of cardiomyogenesis by Cardiogenol C is way more efficient than that achieved by EBs (embryoid bodies) formation and DMSO treatment.

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-221396	N/A	C13H16N4O2	5 mg

• Cardiogenol C hydrochloride
  Induces cardiomyogenesis in embryonic stem cells.

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-214667	671225-39-1	C13H16N4O2 ·HCl	5 mg

• Ciglitazone
  Thiazolidinedione that displays antihyperglycemic activity in genetically obese C57 Bl/6 ob/ob mice. PPARγ agonist. Inhibits HUVEC differentiation and angiogenesis.

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-200902	74772-77-3	C18H23NO3S	5 mg/25 mg

• DAPT
  Potent and specific inhibitor of γ-secretase. It blocks the proteolytic processing of NRADD. Mimics Notch signaling deficiencies at morphological, molecular and biochemical levels.

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-201315	208255-80-5	C23H26F2N2O4	5 mg/25 mg

• Dexamethasone
  Anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein. Causes reduction in cyclin A and Cdk2 activity, inhibition of G₁/S transition in osteoblasts and phosphorylation of Rb protein; induces apoptosis in human thymocytes.

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-29059	50-02-2	C22H29FO5	100 mg/5 g

• Forskolin
  Activates adenylate cyclase and increases intracellular cAMP concentration; inhibits MAP kinase; induces phosphorylation of CREB, connexin 43, Bad, ATF-1, and PKB.

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-3562	66575-29-9	C22H34O7	5 mg/100 mg

• 7-Deacetyl-7-[O-(N-methylpiperazino)-γ-butyryl]-Forskolin Dihydrochloride
  Chemically-modified forskolin with greater stability and water solubility than the parent compound. Activates adenylate cyclase and inhibits 5HT-stimulated inositol phosphate accumulation in muscle cells (smooth).

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-221624	N/A	C29H48N2O7 ·2HCl	5 mg

• IDE 1

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-363282	N/A	N/A	10 mg/50 mg

• 7-Deacetyl-7-O-hemisuccinyl-Forskolin
  A forskolin derivative that can be readily activated and used for preparation of affinity supports and probes. Can be coupled to aminoethyl-agarose via its N-hydroxysuccinimide ester. The immobilized derivative can be used to purify adenylate cyclase; activates adenylate cyclase (EC₅₀ = 50 µM).

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-203959	83797-56-2	C24H36O9	1 mg

• IQ-1
  Modulates Wnt/β-catenin signaling. Targets the PR72/130 subunit of PP2A blocking PP2A/Nkd complex formation, resulting in diminished β-catenin/p300 interaction and increased β-catenin/CBP usage.

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-202665	331001-62-8	C21H24N4O2	10 mg

• Neutral Red Solution

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-281691	553-24-2	C15H17ClN4	100 ml

• NKH 477
  Water-soluble analog of forskolin (sc-3562); potent activator of adenylyl cyclase; with some selectivity for cardiac (type V) adenylyl cyclase. Stimulates bronchodilation (EC₅₀ = 32.6 nM) and is an orally active potent positive chronotrope and hypotensive agent in vivo.

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-204130	138605-00-2	C27H43NO8•HCl	10 mg/50 mg

• Resveratrol
  3,5,4'-trihydroxy-trans-stilbene, a natural polyphenol derived primarily from red wine. Used in stem cell studies to enhance self-renewal and multipotency of mesencymal stem cells (MSC’s). Also used in numerous applications including reducing serum lipids, inhibition of platelet aggregation, as an estrogen receptor agonist, and actions as a chemopreventative agent and antioxidant.

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-200808	501-36-0	C14H12O3	100 mg/500 mg

• Retinoic Acid, all trans
  A retinoid with a wide range of cell regulation activities. The carboxylic acid form of retinol. Binds the RAR and RXR nuclear receptors, initiating transcription events and cell progress.

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-200898	302-79-4	C20H28O2	500 mg/5 g

• SC1 (Pluripotin)
  Small molecule shown to sustain self-renewal of mouse embryonic stem (mES) cells.

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-255607	N/A	C27H25F3N8O2	1 mg

• Stauprimide
  An indolocarbazole small molecule promoter of embryonic stem cell differentiation.

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-202346	154589-96-5	C35H28N4O5	500 µg

• TCS 2210

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-362805	1201916-31-5	C18H17N3O3	10 mg/50 µg

• Thiazovivin

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-361380	1226056-71-8	C15H13N5OS	10 mg

• Tranylcypromine
  An irreversible inhibitor of monoamine oxidase (MAO), and an inhibitor of CYP25A6 and histone demethylase BH110/LSD1. Effective inhibitor of histone demethylation and can antagonize the effects of phenylephrine.

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-200572	13492-01-8	C18H22N2 ·H2SO4	1 g/5 g

• Troglitazone
  Shown to be a potent antiproliferative, apoptosis inducer, antioxidant, and antiinflammatory agent. Also reported to activate PPAR&gamma.

  Catalog #	CAS Number	Molecular Formula	Unit
  sc-200904	97322-87-7	C24H27NO5S	5 mg/25 mg