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PRODUCT NAMECATALOG #DESCRIPTIONCITATIONSRANKING
1-(1-Naphthyl)piperazine·HClsc-201139A mixed modulator of serotonin 5-HT receptors. Demonstrates agonism of the 5-HT1A receptors and antagonism of the 5-HT2A/2C receptors. CAS # 57536-86-4

Clomipramine hydrochloridesc-203898Clomipramine hydrochloride (Anafranil) is an ST (serotonin transporter/SERT), SLC6A2 (norepinephrine transporter/NET), and DAT (dopamine transporter) blocker with Ki of 0.14, 54 and 3 nM, respectively. CAS # 17321-77-6

RS-127445sc-364604RS-127445 is a high affinity 5-HT2B receptor antagonist with modest efficacy against 5-HT2A/C and 5-HT5/6/7. CAS # 199864-87-4

1-Methylpsilocinsc-2037641-Methylpsilocin is a potent and selective SR-2C agonist. CAS # 1465-16-3

Citalopram hydrobromidesc-203551Citalopram hydrobromide is a salt form of Citalopram (sc-201123). Citalopram is a selective inhibitor of ST (5-hydroxytryptamine/serotonin transporter) and therefore is a potent and selective serotonin reuptake inhibitor. CAS # 59729-32-7

1-Phenylbiguanidesc-222728 CAS # 102-02-3

Mesulergine hydrochloridesc-361251Mesulergine hydrochloride is a D2-like dopamine receptor partial agonist and a SR-2A/SR-2C antagonist. CAS # 64795-35-3

1-Phenylbiguanide hydrochloridesc-2034551-Phenylbiguanide hydrochloride is a SR-3 agonist. CAS # 55-57-2

Indatraline hydrochloridesc-203605Indatraline hydrochloride is a strong monoamine uptake inhibitor which inhibits the transporters ST (serotonin/SERT), DAT (dopamine), and SLC6A2 (noradrenalin/NET). CAS # 86939-10-8

BIMU 8sc-362714BIMU 8 is a potent SR-4 full agonist. CAS # 134296-40-5

2-[1-(4-Piperonyl)piperazinyl]benzothiazolesc-2037672-[1-(4-Piperonyl)piperazinyl]benzothiazole is a SR-4 agonist with moderate activity as a SR-3 antagonist.

Fluoxetine HClsc-201125Fluoxetine is an ST (5-hydroxytryptamine/serotonin/5-HT reuptake) inhibitor. CAS # 56296-78-7

3
2-Methylserotonin·HClsc-2011362-Methylserotonin·HCl is a SR-3 agonist shown to have low binding activity for SR-1A, SR-1B, SR-1C, and SR-2 binding sites. CAS # 78263-90-8

Milnacipran hydrochloridesc-204086Milnacipran inhibits both SLC6A2 (norepinephrine transporter/NET) and ST (norepinephrine transporter/SERT) with IC50 of 77 nM and 420 nM, respectively. CAS # 101152-94-7

3-AQCsc-2037763-AQC is a competitive SR-3 antagonist, almost 100 times more potent than tropisetron, but with widely differing activity in various tissues.

3-Oxo Citalopramsc-209668An intermediate of Citalopram and a potent and selective inhibitor of the 5-hydroxytryptamine transporter (serotonin). CAS # 372941-54-3

4-[3-(Benzotriazol-1-yl)propyl]-1-(2-methoxyphenyl)piperazine oxalatesc-220919Strong pre- and postsynaptic 5-HT1A receptor antagonist.

Sertraline HClsc-201104Sertraline HCl is a selective and potent inhibitor of ST (serotonin transporter), increasing availability of serotonin in the brain. CAS # 79559-97-0

1
4F 4PP oxalatesc-2037824F 4PP oxalate is a selective SR-2A antagonist.

Graminesc-255191 CAS # 87-52-5

B-HT 920sc-203523B-HT 920 is a dopamine D2 receptor agonist, SR-3 antagonist and α2-adrenoceptor agonist. It also displays antiparkinsonian activity. CAS # 36085-73-1

5-Carboxamidotryptamine maleatesc-2034775-Carboxamidotryptamine maleate is a SR-1 agonist with high affinity at SR-1A, SR-1B, SR-1D, SR-5 and SR-7. CAS # 74885-09-9

(5-Hydroxy-1H-indol-3-yl)acetic acidsc-299847 CAS # 1321-73-9

5-Nonyloxytryptamine oxalatesc-2034805-Nonyloxytryptamine oxalate is a selective SR-1B agonist. It is inactive as a SR-1A agonist (Ki at SR-1B = 1 nM, selectivity over SR-1B > 300-fold). CAS # 157798-12-4

Venlafaxine Hydrochloridesc-201102Venlafaxine Hydrochloride is a dual ST and SLC6A2 (serotonin and noradrenalin re-uptake) inhibitor that displays ~ 30-fold higher affinity for ST (SERT) than SLC6A2 (NET). CAS # 99300-78-4

8-Hydroxy-DPAT • HBrsc-2011298-Hydroxy-DPAT HBr is a SR-1A agonist with high affinity for SR-1A and SR-7 subtypes. CAS # 87394-87-4

3
8-Hydroxy-PIPAT oxalatesc-3610908-Hydroxy-PIPAT oxalate is a high affinity SR-1A agonist. CAS # 159651-91-9

(±)α-Methylserotonin maleatesc-201134(±)α-Methylserotonin maleate is a racemic mixture of α-methylserotonin maleate. it is a serotonin receptor agonist with preference for SR-2A, SR-2B, SR-2C. CAS # 304-52-9

Almotriptan Hydrochloridesc-210786A Serotonin 5HT1B /1D-receptor agonist. CAS # 154323-46-3

Altanserin hydrochloridesc-203504Altanserin hydrochloride is a selective and potent SR-2A antagonist. In addition, it can be used to determine malfunction in serotonergic neurotransmission. CAS # 76330-71-7

Amperozide hydrochloridesc-203512Atypical antipsychotic which displays a high affinity for 5-HT2 receptors (Ki = 26 nM) and a low affinity for D2 receptors. Supresses ethanol drinking in genetically ethanol-preferring rats. CAS # 75558-90-6

Urapidil HClsc-200155Urapiidil HCl is an adrenergic α1-AR antagonist and a serotonin 5-HT1A (SR-1A) receptor agonist. CAS # 64887-14-5

Anpirtoline hydrochloridesc-201108Anpirtoline hydrochloride is a selective agonist of SR-1B. It shows strong selectivity at SR-1B over the SR-1A and SR-2 subtypes. Anpirtoline is also described to produce antagonism at the SR-3. CAS # 98330-05-3

AS 19sc-203826AS 19 is reported to be a potent SR-7 agonist.

Asenapine maleatesc-361110Asenapine maleate is an antagonist of noradrenalin, dopamine, 5-HT and histamine receptor subtypes. CAS # 65576-45-6

Azasetron Hydrochloridesc-210852A 5-HT3 receptor antagonist which is used as an anti-emetic. CAS # 123040-69-7

BP 554 maleatesc-203851BP 554 maleate is a selective SR-1A agonist. CAS # 82900-57-0

BRL 15572 hydrochloridesc-202979BRL 15572 hydrochloride is a selective SR-1D antagonist, displaying 60-fold selectivity over SR-1B, and exhibiting little or no affinity for a range of other receptor types. CAS # 193611-72-2

BRL 54443sc-203855BRL 54443 is a potent SR-1E and SR-1F agonist. CAS # 57477-39-1

BRL 54443 maleate saltsc-300302BRL 54443 maleate salt has been shown to be a potent agonist for the 5-HT1E/1F serotonin receptor. CAS # 1197333-54-2

Bupropion HClsc-201121Bupropion HCl is a non-selective inhibitor of dopamine and SLC6A2 (Ki values are 1.4 μM for SLC6A2, 2.8 μM for dopamine, and 45 μM for serotonin). CAS # 31677-93-7

Buspirone hydrochloridesc-202982Buspirone hydrochloride is a SR-1A partial agonist. CAS # 33386-08-2

BW 723C86 hydrochloridesc-203428BW 723C86 hydrochloride is an activator of SR-2B. CAS # 160521-72-2

CGS 12066B dimaleatesc-201106CGS 12066B dimaleate is a pyrroloquinoxaline agonist of SR-1B. It is described to be selective for SR-1B, with a 10-fold selectivity over SR-1A receptor and a 1000-fold selectivity over SR-2C. CAS # 109028-10-6

CGS-12066A maleate saltsc-3003455-HT1B serotonin receptor agonist. CAS # 109028-09-3

Cinanserinsc-201110Serotonin 5-HT2 antagonist. CAS # 1166-34-3

Cinanserin hydrochloridesc-361149Cinanserin hydrochloride is a 5-HT2 antagonist. CAS # 1166-34-3 (non-salt)

cis-Urocanic acidsc-214741This 5-HT agonist is a product of uv isomerization of trans-urocanic acid in skin. This leads to immunosuppression via activation of 5-HT2A receptor. CAS # 7699-35-6

rac-trans-Sertralinesc-212762Used in the treatment of menopause and mood, anxiety, and cognitive disorders CAS # 79836-45-6

Cisapridesc-203894Cisapride is a SR-4 agonist that stimulates intestinal ACh. CAS # 81098-60-4

Nemonapridesc-204123Nemonapride is a highly selective D2DR antagonist and potent SR-1A agonist. CAS # 75272-39-8

3
Citalopramsc-201123A selective inhibitor of the 5-hydroxytryptamine transporter (serotonin) and therefore is a potent and selective serotonin reuptake inhibitor. CAS # 59729-33-8

Citalopram N-Oxidesc-207444A metabolite of Citalopram and a potential selective inhibitor of the 5-hydroxytryptamine transporter (serotonin). CAS # 63284-72-0

CJ 033466sc-205257CJ 033466 is a selective and potent SR-4 partial agonist. It’s selectivity for SR-4 is substantially greater than that of other serotonin receptors and D2 receptors. CAS # 519148-48-2

CP 809101 hydrochloridesc-205277CP 809101 hydrochloride is a potent and selective SR-2C agonist. CAS # 479683-64-2

CP 93129 dihydrochloridesc-203904CP 93129 dihydrochloride is a selective SR-1B agonist. CAS # 127792-75-0

WAY 208466 dihydrochloridesc-361404WAY 208466 dihydrochloride is a high affinity, selective SR-6 (5-HT6) receptor agonist. CAS # 633304-27-5

CP 94253 hydrochloridesc-203905CP 94253 hydrochloride is a potent, selective SR-1B agonist. CAS # 131084-35-0

Cyanopindolol hemifumaratesc-203906Cyanopindolol hemifumarate is a SR-1A and SR-1B antagonist. It is also a β-adrenergic antagonist. CAS # 106469-57-2

Cyproheptadine hydrochloridesc-203557Migraine prophylactic and Non-selective 5HT2 antagonist. CAS # 969-33-5

Demethylchloro Citalopram Hydrochloridesc-207519A derivative of Citalopram and a potentially useful internal standard. CAS # 64372-52-7

Dibenzepine HClsc-201115Dibenzepine HCl is a tricyclic antidepressant used in the treatment of depression especially endogenous depression. CAS # 315-80-0

Didemethylchloro Citalopram Hydrochloridesc-207565A derivative of Citalopram and potentially useful as an internal standard. CAS # 887354-48-5

Quetiapine Fumaratesc-219681Quetiapine fumarate is an inhibitor of D2DR and SR-2A. CAS # 111974-72-2

Dihydroergocristine mesylatesc-201117Dihydroergocristine mesylate demonstrates antagonism at serotonin receptors (SR) and partial agonism/antagonism of dopaminergic and adrenergic receptors. CAS # 24730-10-7

2
Dihydroergotamine Methanesulfonate Saltsc-294343A competitive serotonin antagonist and vasoconstrictor. CAS # 11032-41-0

Dolasetronsc-204733An antiserotonin used as an antiemetic to prevent nausea and vomiting brought on by chemotherapy or general anaesthesia. CAS # 115956-12-2

Eicosapentaenoyl Serotoninsc-358802Eicosapentaenoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin (sc-201460). CAS # 199875-71-3

Pindololsc-204847Pindolol is a SR-1A/SR-1B antagonist with similar affinity for each subtype. CAS # 13523-86-9

Eltoprazine hydrochloridesc-203574Eltoprazine hydrochloride is a SR-1 and SR-2C receptor partial agonist. CAS # 98224-03-4

EMD 386088 hydrochloridesc-203575EMD 386088 hydrochloride is a potent SR-6 receptor agonist that displays selectivity to other serotonin receptors. CAS # 54635-62-0

ent-Frovatriptansc-207622Serotonin 5-HT1B/1D receptor agonist. It is a triptan drug for the treatment of migraine headaches. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head. CAS # 158930-18-8

Roxindole hydrochloridesc-203685Selective and potent presynaptic D-2 dopamine autoreceptor agonist. Inhibits serotonin (5-HT) uptake. CAS # 112192-04-8

Fananserinsc-203951Fananserin is a potent serotonin SR-2A and dopamine D4 antagonist, with efficacy against histamine H1, α1 and SR-1A. CAS # 127625-29-0

Fluperlapinesc-201119Fluperlapine is an atypical antipsychotic agent and ligand for the serotonin receptors 5-HT6/5-HT7. CAS # 67121-76-0

2
Fluvoxamine maleatesc-203582A selective serotonin reuptake inhibitor with high affinity for the 5-HT transporter (Ki = 1.6 nM). CAS # 61718-82-9

SKF 38393 HClsc-203264SKF 38393 HCl is a selective dopamine D1DR agonist that seems to be correlated to induced desynchronization of electroencephalographic activity in rats. CAS # 81633-77-4

GR 113808sc-361189A robust and selective receptor antagonist of SR-4. CAS # 144625-51-4

GR 125487 sulfamatesc-361190GR 125487 sulfamate is a selective and effective receptor antagoonist of SR-4 antagonist. CAS # 144625-67-2

GR 127935 hydrochloride hydratesc-250068A selective, potent and orally active 5-HT1B/1D serotonin receptor antagonist. CAS # 148642-42-6 (anhydrous)

GR 55562 dihydrochloridesc-361196GR 55562 dihydrochloride is a selective SR-1B (SR-1Bβ) antagonist. It has been shown to express weak binding at a number of serotonin receptor subtypes. CAS # 172854-55-6

Granisetron hydrochloridesc-203984Granisetron hydrochloride is a SR-3 antagonist that possesses potent antiemetic activity. CAS # 107007-99-8

Indorenate hydrochloridesc-2040125-HT receptor agonist with high affinity for 5-HT1A receptors (pKd = 7.8) and lower affinity for 5-HT1B and 5-HT2C receptors (pKd values are 5.44 and 6.49 respectively). Possesses anti-hypertensive, anorectic, and anxiolytic activity in vivo. CAS # 72318-55-9

Ipsapironesc-203607Ipsapirone is a SR-1A agonist that has been found to selectively bind SR-1 receptors. It is also an anti-apoptotic agent that augments NF-κB, Bcl-XL, catalase, and XIAP expressions in neurons. CAS # 95847-70-4

Isamoltane hemifumaratesc-203608Isamoltane hemifumarate is a SR-1B antagonist, with approximately 30-fold selective over SR-1B. Isamoltane hemifumarate possesses affinity for β-adrenergic receptors. CAS # 55050-95-8

Ketanserin tartratesc-201131Ketanserin tartrate is a seletive serotonin agonist with reported ability to distinguish between various serotonin receptor subtypes. CAS # 83846-83-7

L-694,247sc-361223L-694,247 is known to be a highly potent and selective SR-1D agonist. CAS # 137403-12-4

Lofepraminesc-203624Serotonin and noradrenalin re-uptake inhibitor (SNRI) that is metabolized to desipramine (sc-200158, sc-207535). Produces inhibition of liver tryptophan pyrollase activity in vitro and displays antidepressant properties in vivo.Lofepramine has also been shown to be effective against Multiple Sclerosis in combination with L-phenylalanine. CAS # 23047-25-8

LP 12 hydrochloride hydratesc-300940This product is a 5-HT7 receptor agonist found to display selectivity over D2, 5-Ht1A and 5-HT2A.

Zotepinesc-360895Zotepine is a SR-2A and D2DR inhibitor (Ki values are 0.69 and 2.3 nM respectively). Zotepine is also a potent histamine H1 receptor antagonist (IC50 = 8.0 nM). CAS # 26615-21-4

LP 44sc-224044LP 44 is a high affinity SR-7 agonist. CAS # 824958-12-5

LY 344864 hydrochloridesc-361245LY 344864 hydrochloride is a potent and selective SR-1F agonist. CAS # 186544-26-3

LY-310,762 hydrochloridesc-300941LY-310,762 hydrochloride is a selective and potent SR-1D antagonist. CAS # 192927-92-7

m-Chlorophenylbiguanide hydrochloridesc-203125m-Chlorophenylbiguanide hydrochloride is a potent and selective SR-3 agonist. CAS # 2113-05-5

McN 5652, (+/-)sc-203627Potent, orally active 5-HT uptake inhibitor. Inhibits dopamine and noradrenaline uptake in vitro CAS # 96795-89-0

MDL 11,939sc-204069MDL 11,939 is a potent, selective SR-2 antagonist. CAS # 107703-78-6

2
MDL 72832 hydrochloridesc-204070Potent, selective and stereospecific ligand for central and peripheral 5-HT1A recognition sites. CAS # 113777-33-6

MDL 73005EF hydrochloridesc-204071MDL 73005EF hydrochloride is a potent and selective SR-1A partial agonist with putative anxiolytic properties. CAS # 124756-23-6

MDL-72222sc-201132MDL-72222 is a potent and highly selective antagonist at neuronal 5-hydroxytryptamine receptors, especially SR-3. CAS # 40796-97-2

Melperone hydrochloridesc-204074Melperone hydrochloride is an atypical neuroleptic; 5-HT2A receptor antagonist and D2DR inhibitor. CAS # 1622-79-3

Metergolinesc-204079Antagonist at 5-HT1, 5-HT2, and 5-HT7 serotonin receptors; also 5-HT1D ligand. moderate affinity for 5-HT6 and high affinity for 5-HT7. Analgesic; antipyretic. CAS # 17692-51-2

Methiothepin maleatesc-203630Has moderate affinity for 5-ht5 and high affinity for 5-ht6 and 5-HT7. Also antagonist at 5-HT1 and 5-HT2 Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. CAS # 20229-30-5

Methylergometrine maleatesc-203631Active metabolite of methysergide. Used as an oxytocic. CAS # 113-42-8

Mexiletine hydrochloridesc-203633A use dependent blocker of sodium channels in skeletal muscle tissue. CAS # 5370-01-4

Mianserin hydrochloridesc-3589865-HT2/5-HT1 antagonist. Has moderate affinity for 5-ht6 Non-selective 5-HT2 receptor antagonist. Has moderate affinity for 5-HT6. Antidepressant. CAS # 21535-47-7

Mirtazapinesc-204088Mirtazapine is a potent SR-2 and SR-3 antagonist. In addition, it is a moderately potent α2 adrenoceptor and histamine H1-antagonist. CAS # 85650-52-8

MK 212 hydrochloridesc-203634MK 212 hydrochloride is a SR-2C agonist. CAS # 64022-27-1

ML 10302sc-363330 CAS # 148868-55-7

ML 10302 hydrochloridesc-204089ML 10302 hydrochloride is a potent SR-4 partial agonist that displays > 680-fold selectivity over SR-3. CAS # 148868-55-7

MM 77 dihydrochloridesc-204090MM 77 dihydrochloride is a highly potent and fairly selective SR-1A (postsynaptic) antagonist. CAS # 159311-94-1

MMTCsc-201063MMTC is endogenous to the rat brain and to human urine. As a result of its antioxidant properties, MMTC may be neuroprotective. CAS # 1210-56-6

Mosapride citratesc-203635Mosapride citrate is a selective SR-4 agonist and SR-3 antagonist. CAS # 112885-42-4

N-Desmethyl Escitalopramsc-355637 CAS # 144025-14-9

N-Methylquipazine dimaleatesc-203639N-Methylquipazine dimaleate is a tertiary amine analog of quipazine that is an agonist at SR (SR-3) with an affinity similar to that of quipazine, but which lacks affinity for central SR-1B. CAS # 28614-26-8

NAN-190sc-201138NAN-190 is a SR-1A antagonist. CAS # 115338-32-4

Naratriptan Hydrochloridesc-212362A triptan drug which is used for the treatment of migraine headaches. CAS # 143388-64-1

NAS-181sc-203640NAS-181 is a selective SR-1B antagonist. It increases synthesis and metabolism of serotonin in the brain. CAS # 205242-62-2

Nefazodone hydrochloridesc-203156Nefazodone hydrochloride is a SR-2A antagonist and inhibitor of serotonin and noradrenalin uptake. CAS # 82752-99-6

NPEC-caged serotoninsc-359015NPEC ((N)-1-(2-nitrophenyl)ethyl) is a caged version of serotonin.

NPS ALX Compound 4a dihydrochloridesc-204134NPS ALX Compound 4a dihydrochloride is a competitive SR-6 antagonist displaying preference over other serotonin and D2 receptors. CAS # 299433-10-6

Olanzapinesc-212469Olanzapine is a Serotonin 5-HT2A and D2DR inhibitor with anti-cholinergic activity. CAS # 132539-06-1

Oleamidesc-358696Oleamide acts as an agonist at the CB1 cannabinoid receptor. Oleamide also appears to potentiate the actions of 5-HT on 5-HT2A and 2C receptors. CAS # 301-02-0

Olanzapine Lactam Impuritysc-361832 CAS # 1017241-34-7

Olanzapine Thiolactam Impuritysc-361833 CAS # 1017241-36-9

Ondansetron hydrochloride dihydratesc-205778A serotonin-3 (5-HT3) receptor antagonists, used to prevent radiosurgery-induced nausea and vomiting, along with the modulation of alcohol intoxiccation. CAS # 99614-01-4

Ondansetronsc-201127An antagonist of the serotonin 5-HT3 receptor. Demonstrates anti-emetic effects. CAS # 99614-02-5

Ondansetron hydrochloridesc-204147Ondansetron hydrochloride is a selective SR-3 antagonist. It is antiemetic and preventis emesis induced by cytotoxic drugs and radiation. CAS # 103639-04-9

Org 12962 HClsc-301505Org 12962 HCl is a selective SR-2C agonist. CAS # 210821-63-9

p-MPPF dihydrochloridesc-301510This product is a selective 5-HT1A serotonin receptor antagonist. It has been found to be more potent than p-MPPI. CAS # 223699-41-0

Paroxetine maleatesc-203658Highly potent and selective 5-HT uptake inhibitor that binds with high affinity to the serotonin transporter (Ki = 0.05 nM). CAS # 64006-44-6

Pizotifen malatesc-201143A potent inhibitor of SR-2 receptor activity with potential embryotoxic effects in mice. Also been reported to have acute antagonistic affects on central muscarinic receptors. CAS # 5189-11-7

PNU 109291sc-204203PNU 109291 is a potent and highly selective SR-1D agonist. CAS # 187665-60-7

PNU 142633sc-204204PNU 142633 is a very selective, high affinity SR-1D agonist. CAS # 187665-65-2

PNU 22394 hydrochloridesc-204851PNU 22394 hydrochloride is a potent SR-2C agonist and partial SR-2A/SR-2B agonist. CAS # 15923-78-1

Quipazine dimaleatesc-201145Quipazine dimaleate is a studied SR-3 agonist with a certain amount of SR-2A subtype stimulation as well. CAS # 5786-68-5

5
Hymenidinsc-202177Antagonist of serotonergic receptors. Inhibitor of CDK5/p25 (IC50=4µM) and GSK-3β (IC50=12µM). CAS # 107019-95-4

R-96544 hydrochloridesc-204223R-96544 hydrochloride is a potent, selective SR-2 antagonist. CAS # 167144-79-8

(R)-Citalopram Oxalatesc-219751A derivative of Citalopram and a potential selective inhibitor of 5-hydroxytryptamine transporter (serotonin). CAS # 219861-53-7

Ramosetronsc-204873A serotonin 5HT3 receptor antagonist for the treatment of nausea and vomiting in post-operative cases. CAS # 132036-88-5

Risperidonesc-204881Risperidone is an atypical antipsychotic agent that displays SR-2A inhibition. Risperidone also displays high inhibition of D2DR. CAS # 106266-06-2

Ritanserinsc-203681Potent and long-acting 5-HT2 receptor antagonist (Ki = 0.39 nM). Anxiolytic in vivo. CAS # 87051-43-2

Ro 04-6790sc-204238Ro 04-6790 is a potent and selective SR-6 antagonist. CAS # 202466-68-0

Ro 60-0175 fumaratesc-204890Ro 60-0175 fumarate is a potent, selective SR-2 agonist. Ro 60-0175 shows selectivity for the SR-2C subtype. CAS # 169675-09-6

RS 102221 hydrochloride hydratesc-361310RS 102221 hydrochloride hydrate has been reported to be a selective and potent SR-2C antagonist. CAS # 185376-97-0 (free base)

RS 127445 hydrochloridesc-204244RS 127445 hydrochloride is a high affinity SR-2B antagonist (pKi = 9.5). It displays 1000-fold selectivity for SR-2B with good bioavailability. CAS # 199864-87-4

RS 16566 dihydrochloridesc-361311RS 16566 dihydrochloride has been reported to be a high affinity ligand for the (R)-zacopride binding site. CAS # 175729-69-8

RS 23597-190 hydrochloridesc-203243RS 23597-190 hydrochloride is a selective and competitive SR-4 antagonist. CAS # 149719-06-2

RS 39604 hydrochloridesc-361313Has been shown to be a selective and potent SR-4 antagonist, with a relatively long half life. CAS # 167710-87-4

RS 56812 hydrochloridesc-361315RS 56812 hydrochloride is an extremely potent and selective SR-3 partial agonist. CAS # 143137-35-3

RS 67333 hydrochloridesc-361316RS 67333 hydrochloride is an extremely selective and potent SR-4 partial agonist. CAS # 168986-60-5

RS 67506 hydrochloridesc-361317RS 67506 hydrochloride has been reported to be a selective and potent SR-4 partial agonist. CAS # 168986-61-6

RU 24969 hemisuccinatesc-204896RU 24969 hemisuccinate is a potent SR-1A/SR-1B and moderate SR-2C agonist that may also release serotonin. CAS # 107008-28-6

S 14506sc-205497S 14506 is a full, highly potent and selective SR-1A agonist. CAS # 135721-98-1

(S)-Citalopram N-Oxidesc-212881A derivative of Citalopram and a potential selective inhibitor of the 5-hydroxytryptamine transporter (serotonin). CAS # 917482-45-2

(S)-WAY 100135 dihydrochloridesc-361330(S)-WAY 100135 dihydrochloride has been shown to be a selective and potent SR-1B antagonist. CAS # 133025-23-7 (free base)

Sarpogrelate hydrochloridesc-296371Sarpogrelate hydrochloride is a selective SR-2A antagonist CAS # 135159-51-2

SB 200646 hydrochloridesc-361332SB 200646 hydrochloride is a SR-2C/SR-2B antagonist with a selective affinity for SR-1A. CAS # 143797-63-1

SB 204741sc-224279SB 204741 is a potent, selective SR-2B antagonist. CAS # 152239-46-8

SB 206553 hydrochloridesc-361334SB 206553 hydrochloride is a selective and potent SR-2B/SR-2C antagonist. CAS # 158942-04-2

SB 216641 hydrochloridesc-361335SB 216641 hydrochloride has been reported as a selective SR-1B antagonist with approximately 25-fold selectivity over SR-1D and little or no affinity for a range of other receptor types. CAS # 193611-67-5

SB 221284sc-224281SB 221284 is a potent, SR-2C and SR-2B antagonist. CAS # 196965-14-7

SB 224289 hydrochloridesc-361336SB 224289 hydrochloride has been shown to be a selective SR-1B antagonist. SB 224289 hydrochloride has been found to display more than a 60 fold selectivity for SR-1B over other serotonin receptors. CAS # 180083-23-2

SB 228357sc-361337SB 228357 is a SR-2C and SR-2B receptor antagonist. CAS # 181629-93-6

SB 258585 hydrochloridesc-361339SB 258585 hydrochloride has been found to be a selective and potent SR-6 antagonist. This compound displays more than a 160-fold selectivity over other serotonin receptor subtypes. CAS # 209480-63-7

SB 269970 hydrochloridesc-361342SB 269970 hydrochloride has been shown to be a selective and potent SR-7 antagonist. CAS # 201038-74-6

SB 399885 hydrochloridesc-204264SB 399885 hydrochloride is a potent, brain penetrant, and orally active SR-6 antagonist. CAS # 402713-80-8

SB-258585 dihydrochloridesc-3017895-HT6 serotonin receptor antagonist.

SB203186sc-203257Potent 5-HT4 serotonin receptor antagonist. CAS # 207572-69-8

SDZ 205-557 hydrochloridesc-204273SDZ 205-557 hydrochloride acts as a SR-3 and SR-4 antagonist. CAS # 137196-67-9

SDZ SER 082 fumaratesc-361356SDZ SER 082 fumarate has been reported to be a selectiveSR-2C/SR-2B antagonist with low affinity for SR-1A. CAS # 141474-54-6

Serotonin • HClsc-201146Serotonin • HCl is a tryptophan amino acid neurotransmitter located in the central nervous system, which functions as an endogenous serotonin receptor agonist in a variety of biochemical processes. CAS # 153-98-0

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Spiperone hydrochloridesc-204293Spiperone hydrochloride is an analogue of Spiperone. Spiperone (sc-204293) is an SR-2A and selective D2DR inhibitor. CAS # 749-02-0 (anhydrous)

Spiroxatrine (R 5188)sc-201148Spiroxatrine (R 5188) is a SR-1A antagonist. CAS # 1054-88-2

SR 57227 hydrochloridesc-204301SR 57227 hydrochloride is a potent, selective SR-3 agonist. CAS # 77145-61-0

ST 1936 oxalatesc-364625St 1936 oxalate is a potent and selective agonist of 5-HT6 receptor. ST 1936 oxalate also displays moderate affinity for human α2 adrenergic receptors. CAS # 1210-81-7

Sumatriptan succinatesc-204314A selective 5-HT1 receptor agonist with specificity towards 5-HT1D, 5-HT1B and 5-HT1A, which is carried through cells via liposomes. CAS # 103628-48-4

Tandospirone hydrochloridesc-204320Tandospirone hydrochloride is a SR-1A partial agonist that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors. CAS # 87760-53-0

TCB-2sc-204325TCB-2 is a high affinity SR-2A agonist. CAS # 912440-88-1

Tegaserod, Maleatesc-212993Tegaserod maleate is a SR-4 partial agonist. CAS # 189188-57-6

Tianeptine sodium saltsc-204345A selective facilitator of 5-HT uptake in vitro and in vivo with reported inhibition of dopamine uptake. CAS # 30123-17-2

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Trimipramine Maleate Saltsc-213120A serotonin transport blocker that also blocks norepinephrine uptake. Categorized as a antidepressant. CAS # 521-78-8

Tropanyl-3,5-dimethylbenzoatesc-204357Tropanyl-3,5-dimethylbenzoate is an antagonist of SR-3.

Tropisetron hydrochloridesc-204930Tropisetron hydrochloride is an orally active and potent SR-3 antagonist. It is alos a selective, partial agonist at a7 nicotinic receptors. CAS # 105826-92-4

U 92016Asc-204363Selective 5-HT1A receptor agonist that displays high intrinsic activity (Ki values are 0.4, 7.7 and 36 nM for 5-HT1A, 5-HT1D and D2 receptors respectively and > 1000 nM for 5-HT2, D1, α1 and α2 receptors). Produces hypotension, hypothermia and 5-HT behavioral syndrome following p.o. administration. CAS # 149654-41-1

VER-3323 hemifumarate saltsc-301968This product has been shown to be a 5-HT2C/ 5-HT2B serotonin receptor agonist.

WAY 161503 hydrochloridesc-204392WAY 161503 hydrochloride is a potent and selective SR-2C agonist. CAS # 75704-24-4

WAY 629 hydrochloridesc-204393WAY 629 hydrochloride is a selective SR-2C agonist. CAS # 57756-45-3

WAY-100135sc-364647WAY-100135 is a potent, selective 5-HT1A receptor antagonist (IC50 = 15 nM). It is selective over 5-HT1B, 1C, 2,α1, α2 and D2 receptors (IC50 > 1000 nM). CAS # 149055-79-8

Xaliproden hydrochloridesc-203721Xaliproden hydrochloride is a full agonist at SR-1A. It increases motoneuron survival and promotes effects of NGF on neurite outgrowth in vitro. CAS # 90494-79-4

Y-25130 Hydrochloridesc-201150Y-25130 is a potent and selective SR-3 antagonist with antiemetic effects. CAS # 123040-16-4

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Zacopride hydrochloridesc-203723Zacopride hydrochloride is a highly potent SR-3 antagonist and SR-4 agonist. CAS # 90182-92-6

Zimelidine dihydrochloridesc-203725Selective 5-HT uptake inhibitor; selective over noradrenalin and dopamine uptake (IC50 values are 0.33, 8.2 and 12 μM respectively). Modulates nociception and induces hyperglycemia in vivo, and is an orally active antidepressant. CAS # 56775-88-3

Ziprasidone hydrochloride monohydratesc-204419Ziprasidone hydrochloride monohydrate is an atypical antipsychotic that displays combined SR-2A and D2DR inhibition. CAS # 138982-67-9

Octoclothepin maleate saltsc-253215Octoclothepin maleate salt is an SR-2A inhibitor as well as a D2DR inhibitor. CAS # 4789-68-8

WAY-100635 maleate saltsc-264493WAY-100635 maleate salt is a potent, selective and high affinity SR-2B antagonist. CAS # 634908-75-1

Duloxetine Hydrochloridesc-207599A dual serotonin and norepinephrine reuptake inhibitor (SNRI) that is used in the treatment of stress urinary incontinence, as well as depression. CAS # 136434-34-9

Agomelatinesc-207266This compound is a melatoninergic agonist and selective antagonist of 5-HT2C receptors. It has been shown to be active in several animal models of depression. CAS # 138112-76-2

Trazodone Hydrochloridesc-213097An Antidepressant. CAS # 25332-39-2

CP 135807sc-361155CP 135807 is a selective receptor agonist of SR-1D. CP 135807 has been shown to dose-dependently lower the extracellular serotonin concentration. CAS # 151272-90-1

L-703,664 succinatesc-361225L-703,664 succinate has been shown to be a SR-1D agonist with selectivity over other receptors. CAS # 144776-01-2