Santa Cruz Biotechnology Chemicals Table

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PRODUCT NAME	CATALOG #	DESCRIPTION	CITATIONS
1-O-Hexadecyl-2-acetyl-sn-glycero-3-phospho-(N,N,N-trimethyl)-hexanolamine	sc-202862	PAF antagonist. Shows inhibitory behavior on platelet aggregation, secretion and phospholipid turnover. CAS # 99103-16-9
Araguspongin B	sc-205215	Products isolated from Pacific basin sponges with notable vasodilatory properties. Serve as important signal transduction messengers acting to promote transfer of Ca²⁺ from intracellular stores. Shown to exhibit an antagonizing effect of the calcium-releasing action of inosital 1,4,5-triphosphate at receptor levels in cerebral microsomes. CAS # 123000-02-2
Bis(methylthio)gliotoxin (FR-49175)	sc-201027	Bis(methylthio)gliotoxin (FR-49175) is analog of gliotoxin shown to inhibit PAF-induced platelet aggregation and speed up PAF hydrolysis. CAS # 74149-38-5	5
C-PAF (Carbamyl-PAF )	sc-201025	C-PAF (Carbamyl-PAF) is utilized as a non-hydrolyzable bioactive analog of PAF. It stimulates neutrophil degranulation responses, but resists metabolic inactivation by acetylhydrolase. CAS # 91575-58-5	3
(±) cis-2,5-Bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane	sc-201031	(±) cis-2,5-Bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane is the inactive enantiomer of the platelet-activating receptor (PAFr) antagonist (±) trans-2,5-Bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane. Useful as a negative control. CAS # 116673-47-3	1
CV-3988	sc-201015	CV-3988 is a specific antagonist of PAF binding to the PAF-R. It inhibits PAF-induced platelet aggregation. CAS # 85703-73-7
Eptifibatide	sc-205675	A selective inhibitor of platelet glycoprotein IIb/IIIa receptors. CAS # 148031-34-9
ET-18-OCH3	sc-201021	ET-18-OCH3 is an ether lipid analogue that induces selective apoptosis in tumor cells without affecting normal cells. ET-18-OCH3 has the ability to activate intracellular Fas/CD95 and inhibit activation of p70S6K. CAS # 77286-66-9	1
Ginkgolide B (BN 52021)	sc-201037	Ginkgolide B (BN 52021) is the most potent member of ginkgolide family of PAF-R antagonists. It has been found to accelerate PAF hydrolysis by promoting PAF-AH I α₂ homodimer activity. CAS # 15291-77-7
PCA 4248	sc-203446	PCA 4248 is a dihydropyridine that inhibits PAF in a competitive manner at the PAF-R level. It has been shown to also reduce serotonin secretion caused by PAF. CAS # 123875-01-4
(±) trans-2,5-Bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane	sc-201029	(±) trans-2,5-Bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane is a selective and potent PAF-R antagonist of the diaryl tetrahydrofuran class. It has been reported to block LTP in field CA1 in rat hippocampus. CAS # 116673-45-1