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PRODUCT NAMECATALOG #DESCRIPTIONCITATIONSRANKING
4-(Phenylamino]-1-benzyl-4-piperidinecarboxylic Acid Methyl Estersc-209868Remifentanil CAS # 61085-60-7

5'-Guanidinonaltrindole di(trifluoroacetate) salt hydratesc-252280A selective opioid receptor antagonist. GNTI is five-fold more potent and 500-fold more selective than norbinaltorphimine (nor-BNI) for the opioid receptor in smooth muscle preparations. CAS # 219655-57-9 (anhydrous)

6'-Guanidinonaltrindole ditrifluoroacetate dihydratesc-2548986'-GNTI is a selective agonist of /∂ opioid receptor heterodimers in the spinal cord and has the unique property of selectively activating only opioid receptor heterodimers, but not homomers. 6'-GNT functions as an analgesic demonstrating that opioid receptor heterodimers are functionally relevant in vivo. CAS # 35080-00-3 (anhydrous)

BNTX maleatesc-203850BNTX maleate is a selective δ1 opioid receptor (DOR) antagonist. BNTX maleate inhibits neurogenic ion transport in porcine ileal mucosa. CAS # 129468-28-6

BNTX maleate salt hydratesc-300255BNTX is a selective d1 non peptide opioid receptor antagonist that has been used as a tool to study various functions of opioid receptors.

Butorphan S(+)-mandelatesc-300311Butorphan S(+)-mandelate is an agonist ?/µ opioid receptor.

BW373U86 dihydrobromidesc-300314BW373U86 dihydrobromide is a potent non-peptide agonist for ∂-opioid receptor.

β-Chlornaltrexamine dihydrochloridesc-252572Irreversible ∂, µ and opioid receptor antagonist. CAS # 67025-98-3

(-)-cis-(1S,2R)-U-50488 tartratesc-252609A potent receptor ligand. CAS # 121843-48-9

FITsc-203955FIT is an irreversible δ-opioid receptor (DOR)agonist. FIT acts by alkylating the receptor. CAS # 85951-63-9

HZ2sc-202658A compound that displays a high and selective affinity towards κ opioid receptors (KORs). Mechanistic studies show that the keto carbonyl group of HZ2 binds to a lysine residue of KOR. CAS # 253304-60-8

L-687,384 hydrochloridesc-300863

Levallorphan (+)-tartrate saltsc-252952Partial agonist (antagonist) at µ and δ opioid receptors. CAS # 71-82-9

LPK-26sc-252971LPK-26 is an analog of ICI-199441 and (-)U50,488H (classic kappa agonists). It has extremely high kappa affinity (0.64 nM) and low mu and delta receptor affnities (1170 and 10,000nM). LPK-26 produces an antinocicpetive effect with much higher potency in vivo than morphine or U50488. LPK-26 does not produce physical dependence in mice, but it does suppress naloxone-induced behavioral effects in mice treated with morphine. CAS # 492451-07-7

Metaphit methanesulfonate saltsc-253003An irreversible, non-competitive antagonist at the phencyclidine site on the NMDA receptor. CAS # 99287-12-4

N-Benzylnaltrindole hydrochloridesc-205958N-Benzylnaltrindole hydrochloride is a potent δ-selective opioid receptor (DOR) antagonist with a long duration of action.

N-Methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]phenylacetamide hydrochloridesc-224143A high affinity and selective receptor agonist of κ opioid.

Naloxonazine dihydrochloride hydratesc-253177A potent opioid antagonist that is selective for µ1 opioid receptors. CAS # 880759-65-9 (anhydrous)

Naloxone hydrochloridesc-203153Opioid antagonist. CAS # 357-08-4

Naloxone methiodidesc-255387Quaternary salt of naloxone that is a nonselective antagonist at opioid receptors. It does not cross the blood-brain barrier. CAS # 93302-47-7

Naltriben methanesulfonate hydratesc-301456Naltriben methanesulfonate is a highly selective δ2 opioid receptor (DOR) antagonist. Ligand binding assays show biphasic binding of the antagonist to the single receptor type. CAS # 111555-58-9

Naltrindole isothiocyanate hydrochloridesc-250550A selective irreversible ∂2 opioid receptor antagonist. CAS # 126876-64-0

Opipramol dihydrochloridesc-255404 1/ 2 opioid receptor agonist; an antagonist at D2, 5HT2 and H1 receptors; atypical antidepressant, anxiolytic and antipsychotic. CAS # 909-39-7

SDM25N hydrochloridesc-203694SDM25N hydrochloride is a potent and selective non-peptide DOR antagonist. SDM25N hydrochloride exhibits higher selectivity than naltrindole. CAS # 342884-62-2

Sialorphinsc-253554An analgesic and an exocrine and endocrine signaling mediator, predominantly synthesized in the submandibular gland and prostate of adult rats. Sialorphin prevents spinal and renal NEP from breaking down substance P and Met-enkephalin in vitro. It inhibits the breakdown of substance P with an IC50 of 0.4-1 µM and behaves as a competitive inhibitor. Elicits potent antinociceptive responses in two behavioral rat models of injury-induced acute and tonic pain. Has a role in erectile function most likely through a mechanism that involves relaxation of corporal smooth muscle tissue. CAS # 131748-26-0

SNC 121 Dihydrochloridesc-204291Saturated analog of potent and selective δ opioid receptor agonist SNC 80, with similar binding profile to the parent compound. CAS # 159860-31-8

SNC 162sc-204292SNC 162 is a potent and selective non-peptide δ-opioid receptor (DOR) agonist (Ki = 0.63 nM). SNC 162 shows > 8000-fold selectivity over μ-opioid receptors. CAS # 178803-51-5

SNC 80sc-203267SNC 80 is a highly selective and potent non-peptide δ-opioid receptor (DOR) agonist. CAS # 156727-74-1

Tramadol Hydrochloridesc-205869Analgesic affecting type 3 muscarinic receptor inhibition via quinuclidinyl benzilatereceptors CAS # 36282-47-0

(-)-trans-(1S,2S)-U-50488 hydrochloride hydratesc-258256A potent opioid receptor agonist. A more potent enantiomer of (±)-trans-U-50488. CAS # 114528-79-9 (anhydrous)

(+/-)-trans-U-50488 methanesulfonate saltsc-301928A selective κ-opioid receptor agonist. CAS # 83913-05-7

Trimebutine basesc-204927An opioid receptor agonist. CAS # 39133-31-8

U-62066sc-253816A highly selective opioid receptor agonist; antitussive. CAS # 87151-85-7

U-69593sc-203307Selective κ-opioid receptor agonist. CAS # 96744-75-1

3
Org 27569sc-204151Org 27569 is a CB1 receptor allosteric modulator. Exhibits increased binding of the CB1 agonist. Inhibits CB1 receptor antagonist effectiveness in vitro. CAS # 868273-06-7