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Neuroactive Amino Acids

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PRODUCT NAMECATALOG #DESCRIPTIONCITATIONSRANKING
Biotinyl-Melanin-Concentrating Hormone from salmonsc-319861Has been shown to alter pigmentation through melanosome aggregation within melanocytes of teleost fish in lower vertebrates. However, amphibians and reptiles are shown to to exhibit melanosome dispersion.

Bradyzide di(trifluoroacetate) salt hydratesc-300300Potent, orally active, non-peptide B2 bradykinin receptor antagonist.

DL-2-Amino-4-phosphonobutanoic acid (AP4)sc-200430Broad spectrum EAA ligand and amino-acid derivative. CAS # 20263-07-4

N-Methyl-D-Aspartic acid (NMDA)sc-200458N-Methyl-D-Aspartic acid (NMDA) is the prototypic NMDA receptor agonist, mimics the binding of glutamate. CAS # 6384-92-5

DL-AP4 Sodium saltsc-294386Sodium salt of the broad spectrum EAA ligand, DL-2-Amino-4-phosphonobutanoic acid (AP4) (sc-200430). See separate isomers (sc-200429 and sc-200432).

NPY 5RA972sc-295945NPY 5RA972 is a potent and selective NPY5-R (neuropeptide Y) antagonist (IC50 values are 3.1, >10000, >10000 and >10000 nM for NPY5-R, NPY1-R, NPY2-R and NPY4-R respectively). T CAS # 439861-56-0

RETRAsc-311522This is a mutant p53-dependent activator of p73, an activator of p53-regulated genes, and a suppressor of mutant p53-bearing tumor cells. CAS # 1036069-26-7

S-(+)-PD 123177 trifluoroacetate salt hydratesc-311524This is a selective AT2 angiotensin receptor antagonist. The angiotensin AT2 receptor is an atypical seven transmembrane domain receptor that is coupled to activation of tyrosine phosphatase and inhibition of MAP kinase.

S-PMH sc-311527This augments cell-cell adhesion by enhancing tight and adherens junctions and by abolishing the destabilizing actions of Calcitonin (CT) on these complexes.

[Val5]-Angiotensin II acetate salt hydratesc-301966This product is an angiotensin II analog that is an agonist at1 angiotensin receptors. CAS # 58-49-1 (non-salt)

SF 11sc-311535SF 11 is a neuropeptide Y (NPY) antagonist, specifically for NPY2-R (IC50 = 199 nM). Displays no affinity for NPY1-R at concentrations up to 35 µM. CAS # 443292-81-7

Synthalin sulfatesc-200476Synthalin sulfate a competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor polyamine site. CAS # 111-23-9

GR 231118sc-361194GR 231118 is a potent and selective NPY4-R (neuropeptide Y receptor) agonist. Also shown to be a potent NPY1-R antagonist. CAS # 158859-98-4

Z-L-Abu-CONH-ethylsc-301995Z-L-Abu-CONH-ethyl is a cell-permeable dipeptidyl α-ketoamide that acts as a potent, reversible, and active site inhibitor of calpain-1 and calpain-2 (Ki ~ 250 nM).

Z-L-Abu-CONH(CH2)3-morpholinesc-301996Z-L-Abu-CONH(CH2)3-morpholine is a cell-permeable dipeptidyl α-ketoamide that acts as a potent, highly selective, reversible, and active site inhibitor of Calpain 1 and Calpain 2. CAS # 145731-49-3