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PRODUCT NAMECATALOG #DESCRIPTIONCITATIONSRANKING
1-Ethyl-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-3-pyridinecarbonitrilesc-229787 CAS # 28141-13-1

1-H-Indazole-6-carboxaldehydesc-224686 CAS # 669050-69-5

Cathepsin G Inhibitor Isc-221399Cathepsin G Inhibitor I is a potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G. CAS # 429676-93-7

1,1'-Diethyl-4,4'-cyanine iodidesc-229813A member of the cyanine family of fluorescent dyes that are useful for biomedical imaging. CAS # 4727-49-5

BPIQ-II HCl Saltsc-221375BPIQ-II HCl Salt is a specific and potent inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) (IC50 = 8 pM).

JAK3 Inhibitor, Negative Controlsc-221776JAK3 Inhibitor, Negative Control is a useful negative control for JAK3 inhibitors. CAS # 153437-07-1

PDGFR Tyrosine Kinase Inhibitor Isc-222142PDGFR Tyrosine Kinase Inhibitor I is a cell-permeable and selective, ATP-competitive inhibitor of PDGFR tyrosine kinase. It also potently inhibits Flt3 activity.

PDGFR/VEGFR2 Tyrosine Kinase Inhibitor, 5-Br SU6668sc-222143PDGFR/VEGFR2 Tyrosine Kinase Inhibitor, 5-Br SU6668 is a cell-permeable, potent PDGFR, VEGFR2, and FGFR1 inhibitor.

15(S)-HPETE sc-20096615(S)-HPETE inhibits PGI2 synthase (prostacyclin synthase) and arachidonic acid induced platelet aggregation. CAS # 70981-96-3

CL-387,785sc-221429CL-387,785 irreversibly inhibits EGF-receptor (EGFR) kinase activity as well as EGF-stimulated autophosphorylation of tyrosine residues in the EGFR.

1,5,7-Triazabicyclo[4.4.0]dec-5-enesc-237786 CAS # 5807-14-7

1',3'-Dihydro-5'-methoxy-1',3',3'-trimethyl-6-nitrospiro[2H-1-benzopyran-2,2'-(2H)-indole]sc-237805Photochromic dye CAS # 16331-96-7

1H-Indazole-6-carboxylic acidsc-223199 CAS # 704-91-6

EGFR Inhibitor IIIsc-221580EGFR Inhibitor III is a cell-permeable quinazolinyl-chloroacetamide compound that selectively and irreversibly blocks EGFR autophosphorylation while having no effect on the expression levels of EGFR

2-(Dimethylamino)guanosinesc-220667 CAS # 2140-67-2

2-Aminopurine Ribosidesc-220703A probe of structural dynamicas and charge transfer in DNA. CAS # 4546-54-7

2-Hydrazino Adenosinesc-220737A useful synthetic intermediate in making potent and selective coronary vasodilators. CAS # 15763-11-8

Valinomycinsc-200991Valinomycin is a dodecadepsipeptide and potassium ionophore shown to induce cell death. It has been reported to promote hemolysis in HK erythrocytes and cell death in CHO cells. CAS # 2001-95-8

2-Iodo-5'-ethylcarboxamido Adenosinesc-220744A potent selective adenosine receptor agonist. CAS # 141018-29-3

2-Methyl-5-nitroindolinesc-225477 CAS # 115210-54-3

2-Nitrobenzaldehyde semicarbazonesc-238170A derivatized standard for the assay of nitrofurans in animal tissue by LC/MS. CAS # 16004-43-6

Ionomycin free acidsc-263405An antibiotic selective calcium ionophore, which can extract calcium ions from aqueous phase to organic phase. Can transport other ions such as Mg, Sr, and Ba with a weaker affinity. CAS # 56092-81-0

2-NP-AMOZsc-238185Derivatized standard for the assay of metabolites of furazolidone and furaltadone in animal tissue by LC/MS. CAS # 183193-59-1

2-NP-AOZsc-238186A derivatized standard for the assay of nitrofurans in animal tissue by LC/MS. CAS # 19687-73-1

PD 168393sc-222138PD 168393 is a potent, irreversible, cell-permeable and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity.

2-O-Ethylthymidinesc-220758 CAS # 59495-21-5

2-Thiouridinesc-220766 CAS # 20235-78-3

2,2'-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium saltsc-251817A peroxidase substrate suitable for use in ELISA procedures. CAS # 30931-67-0

2,4,6-Triaminopyrimidinesc-254347 CAS # 1004-38-2

2,6-Dichloropurine-9-β-D-ribosidesc-220812 CAS # 13276-52-3

2'-C-Methyl Cytidinesc-220816 CAS # 20724-73-6

Iromycin Asc-221763Iromycin A is an inhibitor of NOS (nitric oxide synthases) showing selectivity for NOS3 (eNOS) versus NOS1 (nNOS). Iromycin A is an inhibitor of thaxtomine biosynthesis. CAS # 213137-53-2

2'-Thioadenosinesc-220826A potent, selective, and irreversible inhibitor of the catalytic domain of the ErbB subfamily of protein tyrosine kinases. Inactivates ErbB1 (epidermal growth factor receptor) modifying the cysteine residue at the active site. This inactivation is reversed with the addition of 1 mM DTT.

2',3'-Isopropylidene Adenosinesc-220829 CAS # 362-75-4

2',3',5'-Tri-O-acetyl Guanosinesc-220832 CAS # 6979-94-8

3-(2-Indolinyl)-2-(trifluoromethyl)propionic acidsc-231297 CAS # 690632-19-0

Ionomycinsc-3592Ionomycin (Ca) is a highly selective and potent calcium ionophore which serves as a useful tool for increasing intracellular Ca2+ concentrations. A non-fluorescent antibiotic and more effective than A23187 (sc-3591). CAS # 56092-82-1

16
3-Bromo-1H-indazole-5-carboxylic acidsc-231492 CAS # 885521-49-3

3-Chloroindazolesc-231634 CAS # 29110-74-5

3', 5'-Di-O-acetyl-5-bromo-2'-deoxyuridinesc-220909 CAS # 6161-23-5

4-(Dioctylamino)-4'-(trifluoroacetyl)azobenzenesc-238738A dye employed in sensors for amines. CAS # 193154-07-3

4-(β-D-Ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-onesc-220913A useful synthetic intermediate. CAS # 59892-40-9

Nigericin•Nasc-201518Nigericin, a polyether antibioitc K+ and Na+ ionophore, stimulates Ca2+ release from mitochondria and stimulates ATPase activity. CAS # 28380-24-7

1
4-Epitetracycline hydrochloridesc-232640 CAS # 23313-80-6

4-Methylumbelliferyl N-acetyl-β-D-glucosaminidesc-252184Assay for β-N-acetylhexosaminidase. CAS # 37067-30-4

4-Nitrophthalimidesc-238934 CAS # 89-40-7

4,4'-Methylenebis(N,N-dimethylaniline)sc-233050 CAS # 101-61-1

4'-Bromoflavonesc-220999A chemopreventive compound. Strong inducer of phase II detoxifying enzymes. CAS # 20525-20-6

5-Aminoindazolesc-233241 CAS # 19335-11-6

5-Bromo-5-nitro-1,3-dioxanesc-254789An antibacterial agent which is also very effective against yeast and fungi. CAS # 30007-47-7

5-Bromo-7-methyl-1H-indazolesc-226935 CAS # 156454-43-2

5-Bromograminesc-254791 CAS # 830-93-3

5-Bromoindolinesc-226937 CAS # 22190-33-6

5-Chloro-2-methylindolesc-254810 CAS # 1075-35-0

5-Chlorocytidinesc-221019 CAS # 25130-29-4

5-Chlorouridinesc-221022 CAS # 2880-89-9

5-Fluoro Cytidinesc-221026 CAS # 2341-22-2

5-Fluoro-1H-indazolesc-233354 CAS # 348-26-5

5-Nitroindazolesc-239069 CAS # 5401-94-5

5-O-tert-Butyldimethylsilyl-2,3-O-isopropylidene-D-ribosesc-221041 CAS # 68703-51-5

5'-Deoxy-5-fluorocytidinesc-221055A metabolite of Capecitabine. CAS # 66335-38-4

5'-Iodo-5'-deoxy Adenosinesc-221058Precursor for the synthesis of nucleotides, sugar nucleosides and as biologically active substances. CAS # 4099-81-4

5'-O-(4,4'-Dimethoxytrityl)-2,3'-anhydrothymidinesc-221059 CAS # 191474-13-2

5'-O-Trityl-2',3'-dehydrothymidinesc-221063 CAS # 5964-41-0

5'-Tosyl Adenosinesc-221065 CAS # 5135-30-8

Monensin Methyl Estersc-221957Monensin Methyl Ester is a neutral analog of monensin. Monensin Methyl Ester has been used in the preparation of ion-selective membranes for ion-selective electrodes. CAS # 28636-21-7

6-Aminoindazolesc-233530 CAS # 6967-12-0

(+)-6-Aminopenicillanic acidsc-239087 CAS # 551-16-6

6-Bromo-1H-indazolesc-233537 CAS # 79762-54-2

6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purinesc-221089 CAS # 161923-50-8

6-Chloro-6-deoxy-2',3',5'-tri-O-acetylguanosinesc-221094 CAS # 16321-99-6

6-Chloro-7-deaza-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranoysyl)purinesc-221095 CAS # 16754-79-3

6-Chloropurine-9-(2,3-isopropylidene-β-D-ribofuranoside)sc-221098 CAS # 39824-26-5

6-Dimethylaminopurine-9-ribosidesc-221101 CAS # 2620-62-4

7-Deazaguanosinesc-221111 CAS # 62160-23-0

7-Methyl-6-thioguanosinesc-221112 CAS # 55727-10-1

7-Thio-8-oxoguanosinesc-221116 CAS # 122970-43-8

Ferutininsc-221610Ferutinin is a potent, non-steroid agonist for ERα (estrogen receptor) and modest AChE (acetylcholinesterase) inhibitor. CAS # 41743-44-6

8-Aminoguanosinesc-221120A potent inhibitor of purine nucleoside phosphorylase. CAS # 3868-32-4

8-Azido Adenosinesc-221121 CAS # 4372-67-2

8-Benzyloxy-2'-deoxyguanosinesc-221124 CAS # 96964-90-8

8-Bromo-2'-deoxyguanosinesc-221125 CAS # 13389-03-2

8-Quinolinol hemisulfate saltsc-239132 CAS # 134-31-6

9-Deazaguanosinesc-221165 CAS # 102731-45-3

16(R)-Iloprostsc-220643A second generation structural analog of prostacyclin (PGI2) with approximately ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Binds with equal affinity to the recombinant human IP and EP1 receptors with a Kι value of 11 nM. Most preparations of iloprost contain 16(S) and 16(R) stereoisomers. Also inhibits platelet aggregation with an IC50 value of 65 nM.

17-GMB-APA-GAsc-22064417-GMB-APA-GA is an analog of geldanamycin containing a maleimido moiety suitable for preparation of geldanamycin immunoconjugates. 17-GMB-APA-GA is an Hsp90 inhibitor.

A23187 (Mixed Calcium-Magnesium Salt)sc-221193A23187 (Mixed Calcium-Magnesium Salt) is used in cell activation experiments when calcium dose-response data are not required. Ca-Mg ratio ~ 1:1. CAS # 52665-69-7

Acetyl Podocarpic Acid Anhydridesc-221207The liver X receptors (LXRα and LXRβ) are nuclear hormone receptors whose native ligands are oxysterols. Acetyl podocarpic acid anhydride (APD) is a semi-synthetic, potent LXR agonist derived from mayapple extracts. APD acting through LXR in cooperation with the retinoid X receptor (RXR), its heterodimerization partner, induces the expression of the ABCA1 reverse cholesterol transporter. This acts to increase the efflux of cholesterol from enterocytes and thus inhibit the overall absorption of cholesterol (ED50 value of 1 nM). In transient transactivation assays, APD was found to be about 1,000 times more potent and have 8-10-fold greater maximal stimulation of LXR than 22(R)-hydroxy cholesterol (3,4). APD can be used as a positive control for testing of LXR agonists, which have potential as therapeutic agents for the treatment of atherosclerosis. CAS # 344327-48-6

Actinomycin I from Streptomyces antibioticussc-233819 CAS # 18865-46-8

Adenosine 5'-triphosphate (ATP) disodium salt hydratesc-252352A multifunctional nucleotide, which is essential in a variety of cellular functions. The main energy source for cells, via transportation of chemical energy into cells. CAS # 51963-61-2

AG 957, Adamantyl Estersc-221222A lipophilic, adamantyl ester form of tyrphostin AG 957 that displays antiproliferative properties. Shown to be selective and ~3-4 fold more potent than the bcr/abl kinase inhibitor AG 957. Has a longer serum half-life in vivo. Downregulates p210bcr/abl autokinase activity (IC50 = 14 µM). Selectively blocks granulocyte colony formation in CML (chronic myelogenous leukemia) progenitors and inhibits proliferation of K562 cells (IC50 = 9.8 µM) by inducing apoptosis. Reported to retain activity in STI571-resistant and p53-null human leukemia cell lines (IC50 ~0.1-0.25 µM).

Gramicidin Asc-203061An effective antibiotic against gram-positive organisms that is a naturally occurring ion channel-forming pentadecapeptide. CAS # 11029-61-1

2
Amidepsine Asc-221244Amidepsine A is an inhibitor of DGAT (diacylglycerol acyltransferase). CAS # 169181-28-6

Amidepsine Dsc-221245This is an inhibitor of diacylglycerol acyltransferase (DGAT). It shows inhibitory effects in rat liver microsomes (IC50=17.5µM) and Raji cells (IC550=2.8µM). Excessive accumulation of triacetylglycerol is produced by DGAT which may cause fatty liver, obesity and hypertriglyceridemia, and may lead to atherosclerosis, diabetes and metabolic disorders.

Amikacin sulfate saltsc-239222An antibacterial spectrum of Gram-negative and gram-positive bacteria. Aminoglycoside antibiotic ad a derivative of kanamycin. CAS # 149022-22-0

Heracleninsc-391029Apoptosis inducer; induces DNA fragmentation at the G2/M phases of the cell cycle. CAS # 2880-49-1

Aminomalonic Acid Bis(2-aminoethanoic Acid)amide Trifluoroacetic Acid Saltsc-221246

Aminomalonic Acid Bis(3-aminopropionic Acid)amide Trifluoroacetic Acid Saltsc-221247

Aminomalonic Acid Bis(4-aminobutyric Acid)amide Trifluoroacetic Acid Saltsc-221248

Ammonium aluminum sulfate dodecahydratesc-239229 CAS # 7784-26-1

AMO 1618sc-221250Anticholesterolemic agent that can be used as an inhibitor of squalene-2,3-oxide cyclase. Used to study the action of squalene epoxidase in the microsomal cholesterol biosynthetic pathway.

Ampicillin trihydratesc-254945A β-lactam antibiotic; effective against both Gram-negative and Gram-positive bacteria. CAS # 7177-48-2

Angiogenesis Inhibitorsc-221253A cell-permeable indolinone compound that displays anti-angiogenesis properties with a potency that is comparable to that of SU5416. Also acts as a moderate ATP-competitive inhibitor of hEGF-R tyrosine kinase activity. CAS # 186611-44-9

Antibiotic A-23187, 4-Bromosc-200193A divalent cation-specific, ionophoretic antibiotic that acts as a channel for cations such as Mn2+, Ca2+, and Mg2+. CAS # 76455-82-8

Antibiotic TS 155-2sc-362015Antibiotic TS155-2 is a macrocyclic lactone related to hygrolidin but produced by a different Streptomyces species. Antibiotic TS155-2 is reported to be an inhibitor of calcium entry into the cell induced by thrombin stimulation. With the exception of the original patent suggesting hypotensive, anti-platelet, anti-ischaemic and anti-inflammatory activity, no literature investigation of TS155-2 is available. CAS # 303009-07-6

Aristeromycinsc-233890A carbocyclic analogue of adenosine that exhibits antibacterial properties. CAS # 19186-33-5

Aromatase Inhibitor Isc-221269A potent, competitive, nonsteroidal inhibitor of aromatase.

Aβ40 Fibrillogenesis Inhibitorsc-221281Acts as a selective inhibitor of Aβ40 fibrillogenesis and disassembles preformed fibrils.

β-Catenin/Tcf Inhibitor, FH535sc-221398β-Catenin/Tcf Inhibitor, FH535 is a sulfonamide-based and cell-permeable compound that exhibits a dual pathway inhibition against Wnt/β-catenin and PPAR. CAS # 108409-83-2

Bacitracinsc-252399A peptide antibiotic. Inhibitor of peptidoglycan synthesis. Antimicrobial spectrum: Gram-positive bacteria. Mode of Action: Inhibits bacterial cell wall synthesis by inhibiting dephosphorylation of lipid pyrophosphate. Characterization of the bacterial metalloendopeptidase pitrilysin. Strongly inhibits proline endopeptidase from human muscle. CAS # 1405-87-4

Bacitracin zinc saltsc-239267 CAS # 1405-89-6

Batuminsc-221284Antibiotic with high and selective activity against Staphylococcus strains including methicillin-resistant S. Aureus (MRSA) strains in a concentration of 1-10ng/ml. Useful for identification of Staphylococcus species in pure and mixed cultures.

Benzoate Ionophore Isc-233955 CAS # 227092-22-0

Bithionolsc-239383 CAS # 97-18-7

BMSsc-221372A water-soluble reagent that is useful for the reduction of native disulfide bonds in proteins; considered to be superior to DTT.

Bromoxylenol Bluesc-217795Dye Content: 95% CAS # 40070-59-5

CA 1001sc-202512Neutral ionophore with extremely high selectivity for Ca2+ ions. Used in membrane electrodes for Ca2+ determination. Also useful for transport studies in biological membranes CAS # 58801-34-6

2
Cadmium ionophore Isc-252534A selective ionophore for cadmium which is used in solvent polymeric membranes. CAS # 73487-00-0

n-Octylcaffeatesc-221390This is a more potent analog than CAPE. Suppressor of inducible nitric oxide synthase (iNOS; NOS II). Induces apoptosis.

Calcium Ionophore A23187 hemimagnesium saltsc-252540An Ionophore that is highly selective for Ca+2. It potentiates responses to NMDA but not quisqualate. In cell culture, this stimulates nitric oxide production by calmodulin-dependent constitutive nitric oxide synthase. CAS # 72124-77-7

Calcium ionophore IIsc-252541This is suitable for intracellular calcium measurements. Lipophilic ionophore for Ca+2-selective electrodes with a detection limit in the sub-nanomolar range. This is a very good carrier of Ca+2-ions, induces a selectivity in membranes for Ca+2 over Mg+2 by a factor of about 10. CAS # 74267-27-9

Calcium ionophore IVsc-252542An extremely lipophilic C2+-selective ionophore for chemical sensors with long lifetimes. Induces selectivities for Ca over Mg, Na and K (4), 10 (6). CAS # 126572-74-5

Calcium ionophore Vsc-239465Used in highly Ca++-selective membrane electrodes. Exhibit excellent selectivity toward alkali and earth alkali ions (log KPOT(Ca2+,Mg2+ = -5.0)) and extremely high lipophilicity (log PTLC ionophore: 14.6) Neutral ionophore used in a Ca++-selective optode, CAS # 160563-01-9

Calcium ionophore VIsc-234266 CAS # 171979-66-1

Calconcarboxylic acidsc-217820Used with EDTA in the presence of magnesium as an indicator for calcium titrations.; Quality: Contains an inert diluent. CAS # 3737-95-9

Capreomycin sulfate from Streptomyces capreolussc-227572 CAS # 1405-37-4

Cardiogreensc-217845Dye content: ~90% CAS # 3599-32-4

CBFβ Inhibitorsc-221405CBFβ Inhibitor is a cell-permeable thiazolyl compound that binds to PEBP2β (CBFβ) and allosterically disrupts CBFα/Runx1 binding to PEBP2β (CBFβ).

Cefmetazole sodium saltsc-234292 CAS # 56796-39-5

Cefuroximesc-234294 CAS # 55268-75-2

Cellulose triacetatesc-234295 CAS # 9012-09-3

Cephalosporin C zinc saltsc-239482 CAS # 59143-60-1

Cephradinesc-234296 CAS # 38821-53-3

Cercosporin from Cercospora hayiisc-255013A light-induced polyketide phytotoxin reported to produce singlet oxygen when photoactivated. CAS # 35082-49-6

Cesium ionophore IIsc-255014Cesium ionophore ethylammonium-selective membrane electrode CAS # 92003-62-8

Cesium Ionophore IIIsc-234303 CAS # 388569-88-8

CHAPSsc-29088CHAPS is a non-denaturing, zwitterionic detergent often used as a detergent in the solubilization and purification of membrane proteins. Also useful in ion exchange chromatography and isoelectric focusing. CAS # 75621-03-3

Chloramphenicol succinate sodium saltsc-227591Chloramphenicol is a broad spectrum antibiotic which acts by interfering with bacterial protein synthesis, affecting Gram-negative and Gram positive organisms. Salmonella typhi, Haemophilus influenza, Neisseria meningitidus and Bordetella pertussis are susceptible. It has anti-rickettsial activity and is also active against chlamydias of the psittacosis-lymphogranulaoma group. This is obtained from cultures of soil bacterium Streptomyces venuzuelae, isolated from the moon snail, Lunatia heros and is produced synthetically. CAS # 982-57-0

Chlorhexidine diacetate salt hydratesc-252569Cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilization of the outer bacterial membrane. It is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs. CAS # 56-95-1

Chlorhexidine digluconate solutionsc-252570A bis(biguanide) family cationic broad spectrum antibiotic. Very effective against bacteria such as Propionibacterium, Selenomonas, and cocci resembling Veillonella. CAS # 18472-51-0

Nonactinsc-203164A cyclic ionophore and part of the macrotetrolide antibiotics family. The ionophore is commonly produced by several species of Streptomyces which selectively binds K+ and NH4+. Contains many biological and bioassay functions. CAS # 6833-84-7

Chloride ionophore IVsc-234313 CAS # 187404-67-7

Chloroparaffinsc-234341 CAS # 85422-92-0

Chromotrope 2Bsc-252605CI: 16575 CAS # 548-80-1

Chromotrope FBsc-217890Color Index: 14720 Dye Content: 50% CAS # 3567-69-9

Colistin sodium methanesulfonatesc-252624 Binds to lipids on the cell cytoplasmic membrane of Gram-negative bacteria and disrupts the cell wall integrity. Antimicrobial spectrum: Gram-negative bacteria. Cyclopolypeptide antibiotic. Endotoxin-binding capacity. CAS # 8068-28-8

Colominic acid sodium salt from Escherichia colisc-239576 CAS # 70431-34-4

1
Copper(II) ionophore Isc-252632A neutral ionophore for Cu2+-selective polymer membrane electrodes. CAS # 125769-67-7

Coumarin 343sc-252639Suitable as a laser dye. Dye content 97 % CAS # 55804-65-4

Coumarin 6sc-217955Coumarin 6 is fluorescent probe used as a Laser dye. CAS # 38215-36-0

Coumarin 7sc-252640Suitable as a laser dye CAS # 27425-55-4

Crocinsc-217957The coloring principle of saffron which comes from the styles of Crocus sativus, Iridaceae. Crocin as well as its aglucone derivative, crocetin dimethyl ester, play a crucial role in the sex process of algae of the Chlamydomonas group. CAS # 42553-65-1

Curvulinsc-221444Phytotoxin. Inhibits microtubule assembly. Similar to Curvularin. CAS # 19054-27-4

Cyanide Ionophore IIsc-239593Used in preparing membrane sensors for cyanide ions. CAS # 1661-03-6

Cyanine 3 Bisfunctional MTSEA Dye, Potassium Saltsc-217963A fluorescent dye that is thiol reactive and water soluble.

Cyanine 3 Maleimide, Potassium Saltsc-217964Cyanine 3 Maleimide, Potassium Salt is a water soluble, thiol-reactive fluorescent reagent. Suggested to be used for protein and peptide labeling.

Cyanine 3 Monofunctional Bihexanoic Acid Dye, Monosuccinimidyl Ester, Potassium Saltsc-217965A fluorescent dye that is amine reactive and water soluble.

Cyanine 3 Monofunctional Bihexanoic Acid Mono-MTSEA Dye, Potassium Saltsc-217966A cyanine 3 bihexanoic acid fluorescent dye that is thiol reactive and water soluble.

Cyanine 3 Monofunctional Hexanoic Acid Dye Ethylenediamine Amide Potassium Saltsc-217967A fluorescent dye with an accessable amine linker that is water soluble.

Cyanine 3-Bismaleimide, Potassium Saltsc-217970A fluorescent dye that is thiol reactive and water soluble.

Cyanine 5 Bihexanoic Acid Dye, Potassium Saltsc-217971A fluorescent dye that is amine reactive and water soluble. CAS # 252255-40-6

Cyanine 5 Bihexanoic Acid Dye, Succinimidyl Ester, Potassium Saltsc-217972A fluorescent dye that is amine reactive and water soluble.

Cyanine 5 Bisfunctional MTSEA Dye, Potassium Saltsc-217973A fluorescent dye that is thiol reactive and water soluble.

Cyanine 5 Monofunctional Hexanoic Acid Dye, Potassium Saltsc-217974A fluorescent dye that is thiol reactive and water soluble.

Cyanine 5 Monofunctional MTSEA Dye, Potassium Saltsc-217975A fluorescent dye that is thiol reactive and water soluble.

Diazine Blacksc-218178Dye content 65% CAS # 4443-99-6

Dicloxacillin sodium salt monohydratesc-227816An antibiotic used in the treatment of staphyloccoci resistant to penicillin G. Has bacteriostatic and bacteriocidal actions against most Gram-positive bacteria and Gram-negative cocci. Thought to act by inhibiting transpeptidase, the enzyme responsible for the cross-linking of peptidoglycan during the final stages of synthesis of the bacterial cell wall. CAS # 13412-64-1

CCR4 Antagonistsc-221406CCR4 Antagonist is a cell-permeable diaminoquinazoline compound that acts as a potent antagonist against the G-protein-coupled chemokine receptor CKR-4 (CCR4).

Dihexylaminesc-227862 CAS # 143-16-8

Dihydrostreptomycin sesquisulfatesc-255099Inhibits protein synthesis by interfering with translation. CAS # 5490-27-7

Diisodecyl adipatesc-234699 CAS # 27178-16-1

Dimetridazolesc-239793 CAS # 551-92-8

Dimoxystrobinsc-227914 CAS # 149961-52-4

Direct Blue 71sc-218247A tri-azo dye usedul to stain membrane-immobilized antibodies, proteins and in adsorption studies. Dye content 50%. CAS # 4399-55-7

Disperse Orange 3sc-252759Color Index: 11005 Dye standard for the assay of allergy-inducing in textiles. CAS # 730-40-5

Dodecyl [2-(trifluoromethyl)phenyl] ethersc-227961 CAS # 150503-14-3

Duramycin from Streptoverticillium cinnamoneussc-239840This is a polypeptide antibiotic that enhances chloride secretion in airway epithelium. It is used in studies of cystic fibrosis. CAS # 1391-36-2

Eosin Ysc-252776Color Index: 45380:2 Dye content, ~99% CAS # 15086-94-9

Equilinsc-239857 CAS # 474-86-2

Erioglaucine disodium saltsc-218328Color index: 42090 CAS # 3844-45-9

ERK Inhibitorsc-221593A cell-permeable thiazolidinedione compound that shows anti-proliferative properties. Binds preferentially to ERK2 with a KD of ~5 µM and prevents its interaction with protein substrates. Has been shown to block ERK-mediated phosphorylation of ribosomal S6 kinase-1 (RSK-1) and ternary complex factor Elk-1 in HeLa cells, while exhibiting minimal effect on ERK1/2 phosphorylation by MEK1/2. CAS # 1049738-54-6

ERK Inhibitor II, Negative Controlsc-221594A cell-permeable pyrazolopyridazin ol that serves as a (-) control for ERK Inhibitor II. Has been shown to exhibit little activity towards ERK1 and ERK2 or in blocking TGF-β-induced AP-1 activation in Mv1Lu epithelial cells. CAS # 1177970-73-8

Erythromycin A dihydratesc-234871 CAS # 59319-72-1

Erythromycin ethyl succinatesc-234872 CAS # 1264-62-6

Ethyl viologen diperchloratesc-218420Dye Content: 98% CAS # 36305-51-8

Fascaplysinsc-221607Originally isolated from a marine sponge. Selective CDK4/cyclin D1 (IC50=350nM) inhibitor (in an ATP competitive manner). CAS # 114719-57-2

Fast Red ITR Saltsc-255169CI: 37150 CAS # 27580-14-9

FGF Receptor Tyrosine Kinase Inhibitorsc-221612A cell-permeable pyridopyrimidinyl urea compound that acts a strong, ATP-competitive inhibitor of FGFR with excellent selectivity over EGFR, insulin receptor, PDGFRβand c-Src CAS # 192705-79-6

Fialuridinesc-221614A nucleoside analog with anti viral and anti hepatitis B activity. CAS # 69123-98-4

Flumethasone pivalatesc-235147 CAS # 2002-29-1

Fluorescaminesc-218500A non-fluorescent reagent that reacts easily under mild conditions with primary amines in amino acids and peptides to form stable, highly fluorescent compounds. Low background due to hydrolysis. Useful in fluorometric assays of amino acids, protein, and proteolytic enzymes. Adequately blocks newly generated amino termini in protein sequence analyses. CAS # 38183-12-9

Fluorescent Brightener 28sc-218504 Used as a fluorescent brightening agent for polyamide and cellulose fabrics, paper and in detergents and soaps. Also used as a viability stain for the staining of fungi. CAS # 4404-43-7

Fluoride ionophore Isc-252826A selective ionophore used in the determination of fluoride. CAS # 767355-17-9

Formaldehyde-2,4-dinitrophenylhydrazonesc-250022 CAS # 1081-15-8

Gramicidin from Bacillus aneurinolyticus (Bacillus brevis)sc-252865Linear polypeptide antibiotic with a mixture of gramicidin A, B, C, and D. Gramicidin D is a channel-forming ionophore that flip-flops slowly across the membrane and is a known Pgp substrate and surprisingly was found to inhibit Pgp ATPase activity. This inhibition was reversed by other Pgp substrates suggesting a common drug binding site among MDR substrate-type drugs and chemosensitizers. CAS # 1405-97-6

hemi-Calcium bis(2-ethylhexyl)phosphate sc-235277 CAS # 10442-05-4

hemi-Calcium bis[4-(1,1,3,3-tetramethylbutyl)phenyl] phosphatesc-252872Ca++ ion sensor in ion-selective electrodes. CAS # 40835-97-0

HFPBsc-252874A lipophilic ion exchanger for ion-selective membrane electrodes and a lipophilic salt as an additive in membrane electrodes. CAS # 120945-63-3

Hexacyclinic acidsc-221718Antitumor antibiotic. Displays weak cytotoxicity against different tumor cell lines.

Hexadecyltrioctadecylammonium bromidesc-228288 CAS # 179737-01-0

Hispolonsc-221726A polyphenolic compound that induces ROS-mediated apoptosis. Has antiviral activity.

HNMPA-(AM)3sc-221730Cell-permeable analog of HNMPA that yields the parent compound from cleavage by cytosolic esterases. Insulin receptor tyrosine kinase inhibitor and insulin-stimulated glucose oxidation in isolated rat adipocytes. Also have known to inhibit tyrosine autophosphorylation of the human insulin receptor.

HONBsc-218581Decreases racemization in peptide synthesis. Also inhibits formation of N-acylureas. CAS # 21715-90-2

Hurghadolide Asc-221732Cytotoxic, antifungal that disrupts the actin cytoskeleton.

Hydrogen ionophore Isc-235335 CAS # 102-87-4

Hydrogen ionophore IIsc-252893H+-ionophore showing a linear response from pH 2 to 9 in an optimized membrane composition. CAS # 70268-36-9

Hydrogen ionophore IVsc-252895Solvent polymeric membrane electrone neutral hydrogen ion ionophore. CAS # 103225-02-1

Hydrogen sulfite ionophore Isc-250131Ionophore used in Chromoionophore III (ETH, Fluka) based polymeric membrane sensor for hydrogen sulfite. CAS # 151029-29-7

PQ401sc-221738PQ401 is a cell-permeable phenylquinolinyl-urea compound that inhibits IGF-1R autophosphorylation. CAS # 196868-63-0

IL-1R Antagonistsc-221747A cell-permeable, end protected L-valyl derivative modeled on the MyD88-binding sequence of the TIR domain BB-loop of IL-1RI. Specifically inhibits TIR domain-mediated MyD88/IL1-RI interaction without affecting TLR4/MyD88 interaction. Reduces IL-1β-induced fever in mice in vivo and to attenuate IL-1β-induced, but not LPS-induced, activation of MAP kinase signaling cascades in murine lymphocytes and EL4 thymoma cells in vitro.

Indazolesc-235354 CAS # 271-44-3

Indazole-5-carboxaldehydesc-235355 CAS # 253801-04-6

Indirubin Derivative E804sc-221751A cell-permeable indirubin derivative (IDR) that inhibits the Src-Stat3 signaling pathway and displays anti-tumor properties. A potent, ATP-competitive inhibitor of the kinase activities of Src. Decreases tyrosine phosphorylation levels of Src, JAK1, and Stat3 in MDA-MB-468 cells in a time- and dose-dependent manner. Selectively induces apoptosis in cells expressing high levels of active Stat3.

Indoline-7-carboxaldehydesc-250158A useful starter in indoline chemistry. CAS # 143262-21-9

Iodide ionophore Isc-250159An Ionophore used in the detection of I- with Ag+ via titration using an inidicator electrode. CAS # 14039-00-0

IRTK Activatorsc-221765IRTK Activator is a potent and highly selective activator of insulin receptor tyrosine kinase (IRTK; EC50 = 300 nM

IRTK Activator, Negative Controlsc-221766A useful negative control for the IRTK Activator. It does not activate IRTK even at concentrations as high as 100 µM. CAS # 6172-50-5

Isofusidienol Asc-221768Chromone-3-oxepine. Displays antifungal and antibacterial activity against Gram-positive and Gram-negative bacteria.

Isoxanthohumolsc-221771Prenylated flavonoid. Phytoestrogen that induces apoptosis in mature adipocytes.

JMV3002sc-221780JMV3002 is a strong ghrelin receptor antagonist with an IC50 value of 1.1 nM in vitro. At 80 µg/kg, JMV3002 inhibits hexarelin-stimulated food intake by as much as 98% in rats. JMV3002 alone does not elicit growth hormone release nor does it inhibit hexarelin-stimulated growth hormone secretion when tested in infant rats at a dose of 160 µg/kg. CAS # 925239-03-8

PGB1 (Prostaglandin B1)sc-201217PGB1 (Prostaglandin B1) is a nonenzymatic dehydration product of PGE1(sc-201223) and a metabolite of PGA1(sc-201213) that has been shown to modify the pressor responses to sympathetic nerve stimulation. CAS # 13345-51-2

Ki16425sc-221788Ki16425 is a competitive, potent, and reversible inhibitor of EDG-2 (Ki = 0.34 μM), EDG-4 (Ki = 6.5 μM), and EDG-7 (Ki = 0.93 μM). CAS # 355025-24-0

Kirromycin from Streptomyces collinussc-250209An antibiotic that prevents protein formation through inhibition of peptide elongation. CAS # 50935-71-2

Kresoxim-methylsc-228385 CAS # 143390-89-0

Lavendustin A methyl estersc-221837Cell permeable ester of lavendustin A.

Lead ionophore Isc-257666Selective, lipophilic ionophore for lead used in solvent polymeric membrane electrodes. CAS # 72469-41-1

Lead ionophore IIsc-255252Lead ionophore employed in ion-selective polymer membrane electrodes. CAS # 90276-58-7

Lead ionophore IIIsc-257667This is a Lipophilic lead ionophore that is used in optode membranes with subnanomolar detection limits CAS # 141754-61-2

Lead ionophore IVsc-250237An Ionophore which is a highly Pb-selective polymer for membrane electrodes. CAS # 145237-46-3

Levofloxacinsc-252953Bacterial respiratory tract infection antibiotic. CAS # 100986-85-4

Lithium ionophore IIIsc-252962A lithium ionophore used in liquid membrane electrodes for the determination of Li concentration in blood. CAS # 99281-50-2

Lithium ionophore IVsc-257674An ionophore used in the determination of Li+/Na+-concentration ratios in blood serum (therapeutical Li+-range) with solvent polymeric membrane electrodes. CAS # 108083-23-4

Lithium ionophore VIsc-257675A neutral carrier for Li+-ions in PVC ion-selective electrodes with good selectivities over potassium and sodium ions. CAS # 106868-21-7

Lithium ionophore VIIsc-257676Lithium ionophore possessing a high selectivity for Li+ against Na+ and K+ cations. CAS # 106868-29-5

Lithium ionophore VIIIsc-252963A lipophilic, neutral ionophore for lithium ion-selective solvent polymeric membrane electrodes. CAS # 133338-85-9

Luisol Asc-221862Highly oxygenated polyketide lactone.

Magnesium ionophore Isc-252984A neutral synthetic ionophore for Mg2+-selective microelectrodes. The selectivities are sufficient for intracellular measurement of magnesium ion activities, as compared to Na+, K+, Ca2+. Magnesium-selective ionophore for solvent polymeric membrane electrodes. CAS # 75513-72-3

Magnesium ionophore IIsc-252985A new, synthetic neutral ionophore for magnesium. An assay of Mg2+-activity in intracellular liquids with microelectrodes based on Magnesium Ionophore II. CAS # 119110-37-1

Magnesium ionophore IIIsc-252986An onophore used in solvent polymeric membrane electrodes for the assay of Mg2+ activities in blood serum. CAS # 119110-38-2

Magnesium ionophore IVsc-252987A very lipophilic magnesium ionophore. Assay of Mg+2-activity in human blood serum with an optimized liquid polymer membrane electrode. CAS # 135734-39-3

Magnesium ionophore VIsc-250279A Magnesium-selective ionophore. CAS # 151058-38-7

Magnesium ionophore VIIsc-250280A Mg-ionophore containing excellent selectivity. CAS # 156210-12-7

MAP Kinase Antisense Oligonucleotidesc-221871A 17-mer phosphorothioate oligodeoxynucleotide is directed against a sequence that is identical in the p42 and p44 MAP kinases (ERK2 and ERK1) and conserved in human, mouse, and rat. It causes a potent and concentration-dependent decrease in the steady state expression of p42 and p44 MAP kinase in 3T3 L1 fibroblasts and adipocytes. It also prevents differentiation of fibroblasts into adipocytes at 1 µM. Note: 25 nmol = 130 µg.

MAP Kinase Antisense Oligonucleotide, Negative Controlsc-221872A 17-mer phosphorothioate oligodeoxynucleotide with the same nucleotide composition as the MAP kinase antisense oligonucleotide, but in a scrambled sequence. It does not have any effect on MAP kinase expression. Note: 25 nmol = 130 µg.

Martius Yellowsc-218673Dye content: 85% CAS # 605-69-6

Meclocycline sulfosalicylate saltsc-235581 CAS # 73816-42-9

Mensacarcinsc-221881Antitumor compound that has cytotoxic activity.

Mepartricinsc-228453 CAS # 11121-32-7

Methylene Violet 3RAXsc-218835Color index: 50206 Dye Content: 90% CAS # 4569-86-2

MK-2 Inhibitor IIIsc-221948MK-2 Inhibitor III is a cell-permeable pyrrolopyridinyl compound that acts as a potent, selective, and ATP-biniding site-targeting MK-2/MAPKAP-K2 inhibitor. CAS # 1186648-22-5

Monensin decyl estersc-235884 CAS # 164066-23-3

Morantel citrate saltsc-235892 CAS # 69525-81-1

Morantel tartrate hydratesc-235893 CAS # 26155-31-7

Mordant Blue 9sc-218878Color index: 14855 Dye Content: 50% CAS # 3624-68-8

Mordant Brown 1sc-218879 CAS # 3564-15-6

Moxalactam sodium saltsc-250419Potency: ≥830 μg/mg CAS # 64953-12-4

MTSEA Biotinsc-221960Thiol-reactive reagents used for labeling proteins at cysteine residues to study structure and function. CAS # 162758-04-5

N-(+)-Biotinyl-6-aminohexanoic acidsc-221966An active Biotinylation reagent. CAS # 72040-64-3

N-(Iodoacetaminoethyl)-1-naphthylamine-5-sulfonic acidsc-218970N-(Iodoacetaminoethyl)-1-naphthylamine-5-sulfonic acid is a fluorescent sulfhydryl reagent that reacts with thiol compounds to provide photo stable covalent derivatives. CAS # 36930-63-9

N-Acetyl-D-mannosaminesc-221981 CAS # 7772-94-3

N-Benzoylcytidinesc-221994A useful building block for oligoribonucleotide synthesis. CAS # 13089-48-0

N-Benzylidenebenzenesulfonamidesc-250446 CAS # 13909-34-7

N-Boc-indoline-7-carboxaldehydesc-250451A useful bi-functional starter in indoline chemistry and natural product chemistry. CAS # 174539-67-4

N-Boc-indoline-7-carboxylic acidsc-250452A useful starter in indoline based natural product synthesis. CAS # 143262-20-8

N-Carboxymethyl-6-(2,2-dicyanovinyl)-1,2,3,4-tetrahydroquinolinesc-253110Fluorescent molecular rotor CAS # 47072-52-6

N-Phenyl-α-(4-nitrophenyl)nitronesc-255363Indicator electrode for the potentiometric titration of Cu2+ with EDTA. CAS # 3585-90-8

N,N-Dibutylanilinesc-236110 CAS # 613-29-6

N,N-Diethyl-p-phenylenediamine hemioxalate saltsc-236113 CAS # 62637-92-7

N,N'-Bis(salicylidene)-1,2-phenylenediaminesc-219287Dye Content: 97% CAS # 3946-91-6

N1-(6-Indazolyl)sulfanilamidesc-228807 CAS # 13744-68-8

N4-Phthalylsulfathiazolesc-236149 CAS # 85-73-4

Nafcillin sodium salt monohydratesc-236153An antibiotic of the penicillin class that is resistant to beta-lactamase. Offered as the sodium salt monohydrate form. CAS # 7177-50-6

Narasin from Streptomyces auriofacienssc-253180Ionophoric antibiotic which inhibits coccidial infection in poultry and mammals. CAS # 55134-13-9

Nargenicin A1sc-222044Antibiotic against Gram-positive bacteria, specifically Staphylococcus and Clostridia. Effective against multi-resistant strains (penicilline, tetracycline, clindamycin, novobiocin, kanamycin, chloramphenicol, erythromycin). The efficiency of effect is comparable to erythromycin. CAS # 70695-02-2

Nicarbazinsc-250557 CAS # 330-95-0

Nickel ionophore IIsc-228828 CAS # 14609-54-2

Nidulalsc-222074This induces differentiation of human promyelocytic leukemia cells. In COS-7 cells it selectively activates AP-1 dependent signal transduction in a manner which is similar to TPA/PMA. CAS # 185853-14-9

Nisin from Lactococcus lactissc-253191Antibiotic with bactericidal action. Binds to the lipid A portion of bacterial lipopolysaccharides. Induces pore formation in the membranes of cortex cells from excised sorghum roots. Mode of Action: Binds to and interferes with the permeability of the cytoplasmic membrane. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria (requires chelator such as EDTA). CAS # 1414-45-5

Nitrate Ionophore Vsc-228838 CAS # 221011-41-2

Nitrite ionophore Isc-253194An ionophore for nitrite-selective liquid membrane electrodes. CAS # 130549-56-3

Nogalamycinsc-250574An anthracyclic antitumor antibiotic. CAS # 1404-15-5

Nor-R-(+)-SCH-23390 hydrochloridesc-228842 CAS # 106648-57-1

Nor-S-(-)-SCH-23388 hydrochloridesc-228843 CAS # 107128-79-0

(+)-Nutlin-3sc-222085Nutlin-3 is a potent inhibitor of p53-Mdm2 interaction; 150-fold less potent as an inhibitor of p53-Mdm2 interaction than (-)-nutlin-3. CAS # 548472-68-0 (racemic)

(−)-Nutlin-3sc-222086(−)-Nutlin-3 is a cis-imidazoline analog, which inhibits the interaction between the proteins p53 and Mdm2. CAS # 548472-68-0

Octyl 2-Acetamido-2-Deoxy-β-D-Glucopyranosidesc-219464A nonionic detergent for the solubilization of membrane bound protein. CAS # 147126-58-7

Ornithine Decarboxylase Inhibitor, POBsc-222102Ornithine Decarboxylase Inhibitor, POB is a cell-permeable pyridoxyl-ornithine compound.

Oxacillin Sodium Salt Monohydratesc-219502Semi-synthetic antibiotic related to Penicillin. CAS # 7240-38-21

Oxindole Isc-222104Oxindole I is an inhibitor of Cdk1, Cdk2, Cdk4, cyclin B, cyclin D1, cyclin E, Flk-1 and PDGFR.

Oxytetracycline hemicalcium saltsc-250624Inhibits protein synthesis (elongation) by preventing the binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. Mode of Resistance: Active efflux, ribosome protection, and tetracycline inactivation. CAS # 15251-48-6

PD 156273sc-222136A potent inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor. Also inhibits the primary human tumor cell cultures growth.

Penicillin G benzathine saltsc-228904Derivative of an antimicrobial acid produced by certain strains of Penicillium notatum or related moulds. CAS # 1538-09-6

Perchlorate ionophore Isc-253252Used to determine perchlorate in water and human urine. CAS # 84896-72-0

Phenothiazinesc-250686 CAS # 92-84-2

Phloridzinsc-219613It is a dihydrochalcone found in all parts of the apple tree except the mature fruit. Once thought to occur in other Rosaceae such as pear, plum and cherry trees. CAS # 60-81-1

Picrotinsc-228947Non-toxic component of picrotoxin CAS # 21416-53-5

Pipemidic acidsc-236402 CAS # 51940-44-4

Polyinosinic-polycytidylic acid potassium saltsc-202767Specific ligand for TLR3 (Toll-like receptor 3) and MDA5/Helicard . CAS # 31852-29-6

Ponceau Xylidinesc-219629Color index: 16150 Dye content: ≥60% CAS # 3761-53-3

Potassium ionophore IIsc-253306Potassium ionophore for assaying K+-activities. CAS # 69271-98-3

Potassium ionophore IIIsc-253307An ionophore used in solvent polymeric membrane electrodes for the assay of K+, especially in body fluids. CAS # 99348-39-7

Potassium ionophore IVsc-253308An ionophore used in potassium-selective electrodes. CAS # 135463-06-8

Procaine hydrochloridesc-250776A sodium channel blocker, inhibitor of DNA methylation and calcium-induced calcium release in skeletal muscle, downregulator of Wnt, neuronal apoptosis inducer and potently inhibits nicotinic acetylcholine receptors. CAS # 51-05-8

Propionylpromazine hydrochloridesc-250790Propionylpromazine hydrochloride is a D2DR inhibitor. CAS # 7681-67-6

PTP Inhibitor V, PHPS1sc-222226A cell-permeable phenyl hydrazono pyrazolone sulfonate compound that acts as a phosphotyrosine mimetic, active site targeting, competitive, and reversible inhibitor of SHP-2. Shown to inhibit HGF-SF (hepatocyte growth factor/scatter factor)-induced scattering and branching morphogenesis of MDCK epithelial cells at 5 µM and SHP-2 dependent Ras/MAP kinase pathway. Arrests the growth and colony formation of several human tumor cells. CAS # 314291-83-3

Pyrantel (+)-tartrate saltsc-229021Anthelmintic effective against intestinal nematodes including roundworm, threadworm, and hookworm. CAS # 33401-94-4

Pyrantel citrate saltsc-236516 CAS # 5685-86-9

Pyrithioxin dihydrochloridesc-229026 CAS # 10049-83-9

Quinoline Yellowsc-253336Color Index: 47005 CAS # 8004-92-0

Regadenosonsc-222245A selective A2A adenosine receptor agonist in myocardial imaging. CAS # 313348-27-5

RET Receptor Tyrosine Kinase Inhibitorsc-222249RET Receptor Tyrosine Kinase Inhibitor is a cell-permeable ATP-competitive tyrosine kinase inhibitor that is known to target Ret, EGFR, and Met.

Rho Kinase Inhibitorsc-222252A cell-permeable isoquinolinesulfonamide compound that acts as a highly specific, potent, and ATP-competitive inhibitor of G-protein Rho-associated kinase (ROCK). Exhibits a much weaker affinity for other serine/threonine kinases. Shown to selectively block lysophosphatidic acid-induced, but not PDBu-induced, phosphorylation of myristoylated alanine-rich C kinase substrate MARCKS in NT-2 cells.

Ribostamycin sulfate saltsc-236672 CAS # 53797-35-6

Rose Bengal lactonesc-219991A polyhalogenated Fluorescein derivative dye compound. Described to produce cell membrane damage. CAS # 4159-77-7

Rubidium Ionophore Isc-236677 CAS # 721924-26-1

S,S,S-Tris(2-ethylhexyl)phosphorotrithioatesc-236700 CAS # 181629-03-8

S14-95sc-222286This is a potent inhibitor of cytokine-induced activation of STAT1α which leads to the inhibition of inducible expression of proinflammatory enzymes (COX-2, iNOS (NOS II)) and cytokines (TNF-α).

Salbutamolsc-253527An β2-adrenoceptor agonist. CAS # 18559-94-9

Salicylate ionophore Isc-255603Determination of salicylate in physiological and pharmazeutical probes without concentration or pretretment. CAS # 28110-70-5

Salinomycinsc-253530A polyether potassium ionophore antibiotic, which promotes cation movement across biological membranes via exchange-diffusion. CAS # 53003-10-4

Salinomycin monosodium salt hydratesc-236851 CAS # 55721-31-8 (anhydrous)

Samarium(III) Ionophore IIsc-253534A direct assay of Sm(III) in water samples. CAS # 120097-53-2

SB 202474sc-222290A negative control for SB202190 and SB203580 in p38 MAP kinase inhibition studies. CAS # 172747-50-1

SB239063sc-222297A cell permeable inhibitor of p38 MAP kinase, which has an IC50=44nM towards p38α. CAS # 193551-21-2

SC68376sc-222299A potent, reversible, cell-permeable, ATP-competitive, and selective inhibitor of p38 MAP kinase activity in a dose-dependent manner (IC50 = 2-5 µM). Does not inhibit basal ERK or IL-1-induced JNK activity. CAS # 318480-82-9

Silver ionophore IIsc-253559Used in solid PVC membrane electrode. CAS # 130184-19-9

Silver ionophore IVsc-250980Ag-ionophore that has excellent characteristics. CAS # 145237-25-8

Sipholenol Asc-222313Sipholenol is an effective inhibitor of MDR-1 (P-gp). This compound prevents cellular efflux of MDR-1 substrates. CAS # 78518-73-7

Sipholenone Asc-222314This efficiently inhibits the function of P-glycoprotein (Pgp). It is a new reversing agent for treatment of multidrug resistance (MDR) in Pgp-overexpressing tumors. It has antiproliferative activity and is cytotoxic.

Sisomicin sulfate saltsc-236885 CAS # 53179-09-2

Sodium ionophore Isc-258168Neutral ionophore for liquid-membrane electrodes of high selectivity for Na+. CAS # 61183-76-4

Sodium ionophore IIsc-258169Neutral ionophore for liquid-membrane electrodes of high selectivity for Na+/sup>. CAS # 61595-77-5

Sodium ionophore IIIsc-253586Ionophore suitable for the assay of sodium activity in blood, plasma, serum. etc. with a solvent polymeric membrane electrode. CAS # 81686-22-8

Sodium ionophore IVsc-253587Sodium ionophore that shows an extremely high selectivity for Na over K (1000:1). CAS # 172883-29-3

Sodium ionophore VIsc-253588Sodium ionophore for assaying Na+-activities with grafted wire sodium-selective electrodes. It can be used either in a liquid membrane or in a PVC solid membrane. CAS # 80403-59-4

Sodium ionophore VIIIsc-253589A neutral carriers for sodium selective electrodes. CAS # 174752-42-2

Sordarin sodium saltsc-253601An antifungal metabolite possessing a tetracyclic diterpene glycoside structure; a highly potent inhibitor of eukaryotic protein synthesis with selectivity for the fungal translation machinery. CAS # 463356-00-5

Spiramycinsc-251064 CAS # 8025-81-8

SQI-Prsc-222324Synthetic ionophore for sodium. SQI-Pr is effective at concentrations of 1-10 µM in creating Na+ conductance in erythrocytes.

Src Kinase Inhibitor IIsc-222325A substituted triazoloquinoline-1-thione compound that acts as a potent, ATP-competitive, and selective inhibitor of Src family tyrosine kinases. Exhibits little effect against p38 MAPK or FGFR even at concentrations as high as 50 µM.

Sulfabenzamidesc-251079 CAS # 127-71-9

Sulfacetamidesc-251080 CAS # 144-80-9

Sulfachloropyridazinesc-251081 CAS # 80-32-0

Sulfaguanidinesc-251083 CAS # 57-67-0

Sulfaguanidine monohydratesc-236950 CAS # 6190-55-2

Sulfamethazine sodium saltsc-251084 CAS # 1981-58-4

Sulfamethizolesc-251085 CAS # 144-82-1

Sulfamoxolesc-236952 CAS # 729-99-7

Sulfanitransc-251087 CAS # 122-16-7

Sulfaquinoxaline sodium saltsc-251088 CAS # 967-80-6

Sulfate-ionophore Isc-255626Neutral sulfate-selective ionophore for an electrode with remarkable sulfate selectivity. CAS # 37042-63-0

Sulfathiazole sodium saltsc-251089 CAS # 144-74-1

Sulfisomidinsc-236953 CAS # 515-64-0

Sulforhodamine B sodium saltsc-253615Sulforhodamine B sodium salt is a fluorescent rhodamine dye which can be used to quantify cellular proteins in cultured cells. CAS # 3520-42-1

Surfactinsc-255628Lipopeptide antibiotic. Powerful biosurfactant resulting in the lysis of erythrocytes and bacteria. Also a clotting inhibitor. CAS # 24730-31-2

Swinholide Isc-222333A macrolide derived from Swinholide A (sc-205914) that has a hydroxylated side chain. Shows cytotoxic affects in vitro against HCT-116 cells and disrupts the actin cytoskeleton,

Taniaphos SL-T002-1sc-224294 CAS # 1016985-24-2

tert-Butylcalix[4]arene-tetrakis(N,N-dimethylacetamide)sc-251139Starting material for the synthesis of ionophores, e.g. a lead ionophore. CAS # 145237-45-2

Tetrabromophenol bluesc-220215Dye Content: 85% CAS # 4430-25-5

Tetradodecylammonium nitratesc-258223Ion-pair suitable for a nitrate-selective field-effect transistor membrane. CAS # 63893-35-6

Tetraoctylammonium nitratesc-237074 CAS # 33734-52-0

Tetrathiafulvalene 7,7,8,8-tetracyanoquinodimethane saltsc-237081 CAS # 40210-84-2

Thymidine-3',5'-diphosphate, Disodium Saltsc-222354 CAS # 386229-77-2

Thymolphthaleinsc-237105 CAS # 125-20-2

Tiamulinsc-237107 CAS # 55297-95-5

Ticarcillin disodium saltsc-255661β-Lactam antibiotic. CAS # 4697-14-7

Tolnaftatesc-237124 CAS # 2398-96-1

Toluidine Bluesc-253710CI: 52040 CAS # 6586-04-5

Trichodionsc-222368This inhibits NF-κB (IC50=42-84µM), AP-1 (IC50=21µM) and STAT1α mediated gene expression induced by IFN-&gamma: resulting in inhibition of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS; NOS ll) expression. It is cytotoxic.

Tridodecylmethylammonium nitratesc-253743A highly lipophilic electroactive component (nitrate ion-exchange) for solvent polymeric electrodes. Used in ion-selective field effect transistors. and in the determination of nitrate in water, soil extracts and in agriculture by ion-selective electrode. CAS # 13533-59-0

Trifloxystrobinsc-229576 CAS # 141517-21-7

Triflupromazine hydrochloridesc-251335 CAS # 1098-60-8

Trioctyltin chloridesc-253777Chloride ionophore employed in an optical sensor membrane. CAS # 2587-76-0

Tris(2-ethylhexyl)phosphine oxidesc-255705A solvent mediator for serotonin selective electrodes CAS # 2785-32-2

Tryprostatin Asc-222376Diketopiperazine. Arrests cell cycle progression at the G2/M phase. Inhibits the ABC-transporter breast cancer resistance protein and thereby reverses the resistance of cancer cells against antitumor drugs. Inhibitor of MAP-dependent microtubule assembly.

Tylosin solutionsc-253815This is recommended for use in cell culture applications at 1 ml/L. It interferes with bacterial protein synthesis by binding to the 50S subunit. Antimicrobial spectrum: Gram-positive bacteria and mycoplasma. Formulated to contain 8 mg/ml tylosin in 0.9% sodium chloride. CAS # 74610-55-2

Tyrphostin AG 1007sc-222380

Tyrphostin AG 112sc-222381 CAS # 144978-82-5

Tyrphostin AG 114sc-222382

Tyrphostin AG 1290sc-222383

Tyrphostin AG 1385sc-222384

Tyrphostin AG 528sc-222387

Tyrphostin AG 537sc-222388Competitively inhibits EGF receptor kinase autophosphorylation.

Tyrphostin AG 658sc-222390

Tyrphostin AG 698sc-222391 CAS # 134036-52-5

Tyrphostin AG 974sc-222393

Uranyl ionophore Isc-253821An Ionophore is used in electrodes for the detn. of uranyl. CAS # 69844-41-3

Variamine Blue RT Saltsc-220371Color index: 37240 CAS # 4477-28-5

WP631 dihydrochloridesc-222418Synthetic fluorescent bisintercalating anthracycline antibiotic with ultratight binding properties to DNA. Induces apoptosis. Inhibits Sp1-initiated transcription at nanomolar concentrations. Appears to overcome MRP-mediated multidrug resistance.

WP631 dimethanesulfonatesc-222419A bisintercalating antibotic composed of two Daunorubicin molecules. Blocks Sp1 transcription factor activation and inhibits basal transcription by RNA polymerase II.

Ytterbium(III) ionophore Isc-253842Used for the determination of ytterbium in mineral probes. CAS # 125110-14-7

Zinc ionophore Isc-253849Neutral carrier for a Zn-selective electrode. CAS # 1634-02-2

Monensin Asc-362032Monensin A is a polyether antibiotic first isolated from Streptomyces cinnamonensis in 1967. Monensin is a broad-spectrum anticoccicidial antibiotic also exhibiting antifungal and antiviral activity. Monensin A forms complexes with monovalent cations such as Li+, Na+, K+, Rb+, Ag+ and Tl+ and is thus able to transport these cations across lipid membranes of cells, playing an important role as an Na+/H+ antiporter. It blocks intracellular protein transport and is used in the treatment of animals to prevent coccidiosis, promote growth and prevent bloat. Derivatives of monensin, monensin methyl ester and particularly monensin decyl ester, are used in ion selective electrodes. CAS # 17090-79-8