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PRODUCT NAMECATALOG #DESCRIPTIONCITATIONSRANKING
1-Octanesulfonic acid sodium saltsc-251529Ion-pairing reagent for HPLC analysis of peptides and proteins. CAS # 5324-84-5

2-Cyclohexylethyl-4-O-(a-D-glucopyranosyl)-b-D-glucopyranosidesc-280271 CAS # 260804-65-7

4-n-Octylbenzoylamido-propyl-dimethylammoniosulfobetainesc-216955A Zwitterionic detergent that stabilizes and solubilizes integral membrane proteins by breaking aggregates. Useful for protein analysis and characterization using 2D-gel electrophoresis and mass spectrometry. Superior to CHAPS in solubilization. CAS # 216667-49-1

4-Oxo-3-(tetrahydro-furan-2-ylmethyl)-10-oxa-3-aza-tricyclo[5.2.1.0*1,5*]dec-8-ene-6-carboxylic acidsc-316954

APO-10sc-280600Novel non-ionic detergent useful for plasmid DNA isolation. Plasmid DNA isolated using APO-10 does not require the use of phenol/chloroform or proprietary resins. Provides excellent yields of high quality DNA. Allows plasmid DNA to be sequenced through difficult regions without the need to subclone into single-stranded vectors. CAS # 2190-95-6

APO-12sc-280601Non-ionic detergent useful in two-phase separation and purification of proteins. CAS # 871-95-4

ASB-14sc-252390Zwitterionic detergent. Useful for solubilization of proteins, including membrane proteins, for 2D electrophoresis. CAS # 216667-08-2

ASB-16sc-280603A zwitterionic amidosulfobetaine detergent useful for solubilizing proteins visualized by 2D-electrophoresis. The increased solubilization produced by this detergent enables the identification of previously undetected membrane proteins. CAS # 52562-29-5

ASB-C7BzOsc-280604A zwitterionic detergent whivch contains hydroxypropyl group between alkylphenyl hydrophobic tail and ammonio-propane sulfone hydrophilic head. Useful for solubilizing and stabilizing integral membrane proteins by disrupting aggregates. Reported to be compatible with urea (~7 M) and has been used successfully to extract A. thaliana leaf plasma membrane proteins and band III, a 100 kDa erythrocyte polytransmembrane protein, by two-dimensional electrophoresis (2-DGE).

Benzethonium hydroxide solutionsc-280610~1.0 M in methanol Used in scintillation experiments. CAS # 498-77-1

Big CHAPsc-280621Non-ionic detergent analog of CHAPS and CHAPSO with significantly reduced electrostatic interactions that do not interfere in anion exchange chromatography on DEAE-cellulose. CAS # 86303-22-2

Brij 35sc-280628A polyglycol ether which functions as a detergent for the isolation of functional cell membrane complexes. CAS # 9002-92-0

Bt3(1,3,5)IP3/AMsc-280630Novel analogs capable of exhibiting Ins(1,4,5)P3-like agonist or antagonist effects on calcium release are more resistant to hydrolysis and metabolic degradation than IP3 or IP4. Consequently, they can produce a prolonged activation of cellular processes dependent on the Ins(1,4,5)P3 receptor interaction. These tools are important in the elucidation of the molecular interactions of Ins(1,4,5)P3 with its intracellular receptor and with Ins(1,4,5)P3-kinase and 5-phosphatase. Acetoxymethyl esters of inositol phosphate are highly lipophilic. Hence, they easily diffuse through the cell membrane. Note: Each set contains 1 µmol of Bt3(1,3,5)IP3/AM and 10 mg of PLURONIC F-127 detergent to aid in the solubilization of this product.

C12E8sc-280634C12E8 is a non-ionic detergent useful for solubilization of membrane-bound proteins in their native state. CAS # 3055-98-9

Cetyltrimethylammonium Bromidesc-278833A cationic detergent suitable for the isolation of high molecular weight DNA in plants and other organisms. CAS # 57-09-0

CHAPSOsc-280635A unique detergent with high CMC that solubilizes membrane-bound proteins in their native state. Capable of solubilizing opiate receptor to a state exhibiting reversible binding of opiates. Has higher solubility than CHAPS because of its more polar head group. CAS # 82473-24-3

Chenodeoxycholic acid diacetate methyl estersc-280636 CAS # 2616-71-9

Chenodeoxycholic Acid, Sodium Saltsc-280637Bile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets. Induces a permeability transition in freshly isolated rat liver mitochondria. CAS # 2646-38-0

Cholic acidsc-255020Non-denaturing ionic detergent used for extraction of membrane proteins. Bile Acid CAS # 81-25-4

Cholic Acid, Sodium Saltsc-280641Cholic Acid, Sodium Salt is a primary bile acid. CAS # 361-09-1

Choline p-toluenesulfonate saltsc-281523A useful intermediate as well as a choline acetyltransferase (CHAT) substrate. May be used with organic solvents. CAS # 55357-38-5

Cyclohexyl-n-hexyl-β-D-maltosidesc-280651Cyclohexyl-n-hexyl-β-D-maltoside is a detergent designed specifically for the purification and crystallization of membrane-bound proteins in their native state. CAS # 228579-27-9

Cyclohexylmethyl-4-O-(a-D-glucopyranosyl)-b-D-glucopyranosidesc-280652 CAS # 260804-64-6

DDMABsc-280663Water-soluble zwitterionic detergent with properties similar to DDMAU but differing in the length of the polymethylene arm. More efficient for the extraction of mycoplasma membrane antigens under mild conditions than DDMAU. CAS # 15163-30-1

Decyl b-D-maltopyranosidesc-280666 CAS # 82494-09-5

Decyl b-D-thioglucopyranosidesc-280667 CAS # 98854-16-1

Decyl-β-D-1-thiomaltopyranosidesc-280668Detergent for the purification, extraction and solubilization of membrane-bound proteins in the native structure. It increases solubilization by dissociating aggregates and is easily removed by dialysis. CAS # 148565-56-4

Deoxycholic Acid, Sodium Saltsc-280670An ionic detergent for the solubilization of membrane-bound proteins. Reported to induce tyrosine phosphorylation of b-catenin and its subsequent translocation to the nucleus, promoting activation of b-catenin signaling (effective concentration 5-50 µM). CAS # 302-95-4

Diethylene glycol monohexyl ethersc-280674 CAS # 112-59-4

Diethylene glycol monopentyl ethersc-326822 CAS # 18912-81-7

Digitoninsc-280675Digitonin is a non-ionic detergent commonly used to solubilize membrane-bound proteins. CAS # 11024-24-1

Digitoxigeninsc-255098 CAS # 143-62-4

Dimethylethylammoniumpropane sulfonatesc-300486This product is a compound used for non-denaturing protien purification. CAS # 160255-06-1

Eicosyltriethylammonium Bromidesc-280683 CAS # 75222-49-0

ELUGENT Detergent, 50% Solutionsc-280685ELUGENT Detergent, 50% Solution is a non-ionic detergent composed of a mixture of alkyl glucosides. CAS # 132778-08-6

Ethylene glycol monodecyl ethersc-280713Non-ionic surfactant which effectively releases histamine from rat peritoneal mast cells. CAS # 23238-40-6

Ethylene glycol monododecyl ethersc-280714Non-Ionic surfactant. CAS # 4536-30-5

Ethylene glycol monohexadecyl ethersc-257517 CAS # 2136-71-2

Ethylene glycol monohexyl ethersc-280715 CAS # 112-25-4

Ethylhexadecyldimethylammonium bromidesc-280717 CAS # 124-03-8

GENAPOL X-080, 10% Solution, Sterile-Filteredsc-280726GENAPOL X-080, 10% Solution, Sterile-Filtered detergents have been purified for the isolation of membrane proteins (cloud point: 74–76°C in water; HLB number: 13-14). CAS # 9043-30-5

GENAPOL X-100, 10% Solution, Sterile-Filteredsc-280727GENAPOL® X-100, 10% Solution, Sterile-Filtered are polyglycol ethers with the general formula R-CH2-O-(CH2CH2O)nH, where n = the number of ethylene oxides.

Glucopone 600 CS UP solutionsc-252856 CAS # 170905-55-2

Glycocholic Acid, Sodium Saltsc-280754Formed by the conjugation of cholic acid with glycine. CAS # 863-57-0

Glycodeoxycholic Acid, Sodium Saltsc-280755Glycodeoxycholic Acid, Sodium Salt induces apoptosis in hepatocytes by a mechanism associated with DNA cleavage by endonucleases. CAS # 16409-34-0

Hexadecyltrimethylammonium p-toluenesulfonatesc-280770 CAS # 138-32-9

Hexaethylene glycol monodecyl ethersc-280771 CAS # 5168-89-8

Hexaethylene glycol monododecyl ethersc-252881A non-ionic surfactant which effectively releases histamine from rat peritoneal mast cells. CAS # 3055-96-7

IGEPAL CA-630sc-280818Nonionic, non-denaturing detergent suitable for solubilization, isolation and purification of membrane protein complexes and in two-dimensional (2D) gel electrophoresis. CAS # 9036-19-5

Igepal CO-630sc-358253 CAS # 68412-54-4

Lauroyl-DL-carnitine chloridesc-280906A zwitterionic acylcarnitine detergent. Demonstrates enhancement of mucosal absorption of molecules. CAS # 14919-37-0

Lauroylsarcosine, Sodium Saltsc-280907Ionic detergent used to purify membrane proteins. Also decreases transcription efficiency. CAS # 137-16-6

LPD-12sc-280941A water soluble, amphiphilic α-helical lipopeptide detergent (LPD) that forms small micelles and effectively mimics lipid bilayers (solubility in PBS ~ 40 mM). Shown to not only solubilize but also stabilize bacteriorhodopsin, lactose permease and E. coli PagP protein ([LPD] ~ 250 µM and [protein] ~ 22 µM) by forming complexes and precluding aggregation. Useful for NMR and X-ray structural studies of membrane proteins.

MEGA-8sc-280957MEGA-8 is a water-soluble detergent with nondenaturing properties. Can be readily removed by dialysis. MEGA 8 is also a useful reagent for membrane research. CAS # 85316-98-9

MEGA-9sc-280958Water-soluble detergent with nondenaturing properties. Can be readily removed by dialysis. Useful reagent for membrane research. CAS # 85261-19-4

Methoxypolyethylene glycol 350sc-255268 CAS # 9004-74-4

Methylbenzethonium chloridesc-280989 CAS # 25155-18-4

N-Decanoyl-N-methylglucaminesc-281067Water-soluble detergent with high solubilizing power and nondenaturing properties. Can be readily removed by dialysis. Useful reagent for membrane research. CAS # 85261-20-7

n-Dodecyl α-D-maltosidesc-281069 CAS # 116183-64-3

n-Dodecyl-b-D-maltosidesc-281071n-Dodecyl-β-D-maltoside is a non-ionic surfactant, forms useful micelles for stabilization and solubilization of proteins. CAS # 69227-93-6

n-Dodecyl-β-D-glucopyranosidesc-281070Highly purified non-ionic detergent for solubilization of membrane-bound proteins in their native state. CAS # 59122-55-3

n-Heptyl-β-D-glucopyranosidesc-281075n-Heptyl-β-D-glucopyranoside is a non-ionic detergent useful for the solubilization of membrane-bound proteins in their native state and for the preparation of lipid vesicles. CAS # 78617-12-6

n-Hexadecyl β-D-maltosidesc-281076Detergent for the purification, extraction and solubilization of membrane-bound proteins in the native structure. It increases solubilization by dissociating aggregates and is easily removed by dialysis: N.C. Robinson et al., Biochemistry, 24, 6298 (1985) CAS # 98064-96-1

n-Hexyl-β-D-glucopyranosidesc-281077Mild non-ionic detergent. CAS # 59080-45-4

n-Nonyl-β-D-glucopyranosidesc-281084 CAS # 69984-73-2

N-Octanoyl-β-D-glucosylaminesc-281086 CAS # 134403-86-4

n-Octanoylsucrosesc-281088n-Octanoylsucrose is a non-ionic detergent useful for solubilization of membrane-bound proteins in their native state.

n-Octyl-β-D-glucopyranosidesc-281091n-Octyl-β-D-glucopyranoside is a non–ionic detergent intended for solubilizing membrane–bound proteins in their native state and for the preparation of lipid vesicles. CAS # 29836-26-8

n-Octyl-oligo-oxyethylenesc-286437Detergent for solubilization, purification and crystallization of membrane proteins. CAS # 27252-75-1

n-Octyl-β-D-maltopyranosidesc-281089Water-soluble non-ionic detergent suitable for solubilization and isolation of membrane proteins. Closely related to n-octyl-β-D-glucopyranoside (CMC 20-25 mM) and n-dodecyl-β-D-maltopyranoside (CMC 100 - 600 µM). Contaminants: n-octanol < 0.05% (HPLC). Aggregation number 6. CMC 19.5 mM. CAS # 82494-08-4

n-Octyl-β-D-thioglucopyranosidesc-281090Non-ionic detergent that has been used to isolate membrane proteins from E. coli without inactivation. Stable in aqueous solution and easily removed by dialysis. Highly purified and intended for use as a detergent to solubilize membrane-bound proteins in their native state. CAS # 85618-21-9

n-Octylglucosidesc-29103Mild, non-denaturing detergent for the solubilization and reconstitution of membrane proteins. CAS # 29836-26-8

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n-Undecyl β-D-glucopyranosidesc-281096 CAS # 70005-86-6

N,N-Dimethyloctadecylamine N-oxide solutionsc-281100Non-ionic surfactant CAS # 2571-88-2

NDSB-195sc-205912NDSB-195 is a member of the class of nondetergent sulfobetaines. Unlike CHAPS and other zwittergents, NDSBs are nondenaturing even at 1 M concentrations. CAS # 160255-06-1

NDSB-211sc-205913A non-detergent sulfobetaine useful for protein solubilization and stabilization of halophilic proteins. CAS # 38880-58-9

NDSB-221sc-222051A non-detergent sulfobetaine (NDSB) useful for the renaturation of unfolded proteins. CAS # 160788-56-7

Sodium tetradecyl sulfatesc-253187Alkyl sodium sulfate surfactant. CAS # 139-88-8

NDSB-256sc-204120Nondetergent sulfobetaines class member; nondenaturing. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. CAS # 81239-45-4

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NDSB-256-4Tsc-222052NDSB-256-4T is a non-detergent sulfobetaine (NDSB) that prevents protein aggregation and facilitates protein-folding, presumably by interacting with the early folding intermediates. CAS # 570412-84-9

Nonaethylene glycol monododecyl ethersc-281106 CAS # 3055-99-0

Nonidet® P40 (substitute)sc-29102Nonionic, non-denaturing detergent suitable for for solubilizing and isolation of membrane proteins. Chemically indistinguishable from Nonidet P-40, which is no longer commercially available. CAS # 68412-54-4

Nonyl-β-D-1-thiomaltosidesc-281107n-Nonyl-β-D-thiomaltoside is a newly developed detergent whose lipophilic moiety is maltose. This reagent is suitable for isolating proteins inside of cell membranes. The activity of protein isolated using n-Nonyl-β-D-thiomaltoside is higher than those isolated using n-Octyl-β-D-thioglucoside or n-Heptyl-β-D-thioglucoside. As the CMC value of this detergent is 2.4 mM, it is easy to remove from protein solutions by dialysis. CAS # 148565-55-3

Nonylphenyl-polyethyleneglycol acetatesc-281568Plasticizer for embedding bone-containing tissue for histochemistry. CAS # 54612-40-7

NP-40 Alternativesc-281108NP-40 Alternative is an alternative form of Nonidet P-40, which functions as a polyglycol ether (nonionic) surfactant that is useful in isolating and purifying membrane proteins in two dimensional gel electrophoresis. CAS # 9016-45-9

Octaethylene glycol monodecyl ethersc-281111 CAS # 24233-81-6

Octaethylene glycol monooctadecyl ethersc-281112 CAS # 13149-87-6

Octylthiogalactosidesc-281113Non ionic detergent used for solubilizing proteins. CAS # 42891-16-7

Oxyphenonium bromidesc-281114A quaternary ammonium antimuscarinic & anticholinergic agent with peripheral side effects similar to those of Atropine. Used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms. Has also been used in the form of eye drops for mydriatic effect. CAS # 50-10-2

Pentaethylene glycol monodecyl ethersc-281125 CAS # 23244-49-7

Pentaethylene glycol monooctyl ethersc-281126 CAS # 19327-40-3

PLURONIC F-127, 10% Solution, Sterile-Filteredsc-281131A non-ionic detergent useful for isolation of membrane proteins. Has been used to solubilize large dye molecules in physiological media. Because of its low UV absorbance, can be used in protocols that require UV monitoring of the solubilized proteins. CAS # 9003-11-6

Polyoxyethylene (10) tridecyl ethersc-281132 CAS # 24938-91-8

Polyoxyethylene (25) propylene glycol stearatesc-281133 CAS # 37231-60-0

Polyoxyethylenesorbitan monopalmitatesc-255442Non-ionic detergent used for cell lysis, cell fractionation and nuclei isolation. Special Molecular Weight Info: estimated mol wt 1277 CAS # 9005-66-7

Polysorbat 60sc-281134 CAS # 9005-67-8

Polysorbate 80sc-255444Non ionic detergent used for cell lysis, nuclei isolationand cell fractionationBulk pricing available CAS # 9005-65-6

Saponinsc-280079A secondary metabolite, which facilitates the penetration of proteins through the cell membrane. CAS # 8047-15-2

Sodium 1-heptanesulfonatesc-253570Ion-pairing reagent for HPLC, including analysis of proteins and peptides. CAS # 22767-50-6

Sodium deoxycholate monohydratesc-253579This is a powerful solubilizating agent that is used in the solubilization of estrogen synthetase in human placental microsomes. CAS # 145224-92-6

Sodium taurodeoxycholate hydratesc-253596A bile salt-related, anionic detergent used for isolation of membrane proteins (including inner mitochondrial membrane proteins). CAS # 207737-97-1

Sodium taurohyodeoxycholate hydratesc-281149 CAS # 38411-85-7

Sorbitan monolauratesc-281151Monoester of lauric acid and hexitol anhydrides derived from sorbitol. CAS # 1338-39-2

Sorbitan monostearatesc-281152Partial ester of stearic acid with sorbitol and its mono- and dianhydrides. CAS # 1338-41-6

Sorbitan monooleatesc-281153Partial oleate ester of sorbitol and its mono- and dianhydrides. CAS # 1338-43-8

Sucrose monocapratesc-281159 CAS # 31835-06-0

Sorbitane Trioleatesc-281154Mixture of the partial tri-esters of sorbitol and its mono- and di-anhydrides with oleic acid CAS # 26266-58-0

Sucrose monolauratesc-281160A non-ionic detergent for the solubilization of membrane proteins and growth inhibitor of Listeria monocytogenes. CAS # 25339-99-5

Taurochenodeoxycholic Acid, Sodium Saltsc-281162Detergent useful for the solubilization of lipids and membrane-bound proteins. Inhibits Na+-dependent taurocholate transport in the intestine. CAS # 6009-98-9

Sodium taurocholatesc-281163Sodium taurocholate is a detergent useful for the solubilization of lipids and membrane-bound proteins. Aggregation number 4. CMC 3–11 mM. Micellar weight 2100. pKa 1.9. CAS # 145-42-6

Taurodeoxycholic Acid, Sodium Saltsc-281164Taurodeoxycholic Acid, Sodium Salt is a detergent useful for the solubilization of lipids and membrane-bound proteins. Aggregation number: 6. CMC 1 - 4 mM. pKa 1.9. CAS # 1180-95-6

Tauroursodeoxycholic Acid, Sodium Saltsc-281165Detergent useful for the solubilization of lipids and membrane-bound proteins. CAS # 14605-22-2

Tergitol®sc-253623Polyglycol ether (nonionic) surfactants. CAS # 68131-40-8

Tergitol® NP-10sc-281166A polyglycol ether (nonionic) surfactant. CAS # 127087-87-0

Tetraethylene glycol monododecyl ethersc-281576A well-characterised, non-ionic surfactant commonly used in industrial formulations. CAS # 5274-68-0

Tetraethylene glycol monohexadecyl ethersc-281577Surfactant used in gel-emulsion preparation. CAS # 5274-63-5

Tetraethylene glycol monooctyl ethersc-253671Useful in solubilizing membrane proteins. CAS # 19327-39-0

Thonzonium bromidesc-281578Mono-catioinc detergent that has been used in the preparation of pDNA condensed particles. CAS # 553-08-2

Triethylene glycol monodecyl ethersc-281176Non-ionic surfactant. Has been used to study the sodium current of the squid giant axon; Effectively releases histamine from the cell granules of rat peritoneal mast cells CAS # 4669-23-2

Triethylene glycol monooctyl ethersc-253750Useful for solubilising membrane proteins. CAS # 19327-38-9

Tris dodecyl sulfatesc-281179Buffer. Used in conjunction with 4-picoline laury sulfate in a two-dimensional electrophoresis. CAS # 50996-85-5

TRITON X-100 Detergent, Hydrogenatedsc-281181Nonionic detergent used for the solubilization of membrane-bound proteins. Lacks the UV absorbance and fluorescence of TRITON X-100 Detergent which causes interference in spectophotometric monitoring and assays. CMC 250. CAS # 101013-07-4

Triton X-100sc-29112Triton X-100 is a non-ionic surfactant and emulsifier widely used for the solubilization of membranes and recovery of membrane components under mild, non-denaturing conditons. CAS # 9002-93-1

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Tween 85sc-296674 CAS # 9005-70-3

Tyloxapolsc-255711A nonionic liquid polymer of the alkyl aryl polyether alcohol type. Employed as a surfactant. CAS # 25301-02-4

ZWITTERGENT 3-08 Detergentsc-281190 CAS # 15178-76-4

ZWITTERGENT 3-10 Detergentsc-281191 CAS # 15163-36-7

ZWITTERGENT 3-12 Detergentsc-281192 CAS # 14933-08-5

ZWITTERGENT 3-14 Detergentsc-281193 CAS # 14933-09-6

ZWITTERGENT 3-16 Detergentsc-281194 CAS # 2281-11-0