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Antiprotozoals

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PRODUCT NAME	CATALOG #	DESCRIPTION	CITATIONS	RANKING
Buparvaquone	sc-210970	An analog of the antimalarial hydroxynaphthoquinones. It is a tert-butyl derivative of Parvaquone which exhibits Antiprotozoal (Theileria) properties. CAS # 88426-33-9
Halofuginone Hydrochloride	sc-211579	A halogenated analog of the antimalarial alkaloid febrifugine with antiprotozoal, antiangiogenic, and antiproliferative effects. CAS # 1217623-74-9
Nifurtimox	sc-212392	A nitrofurane derivative antiprotozoal that shows anti Trypanosoma cruzi activity through bioreduction of the nitro-group and dependent on redox cycling with O₂. CAS # 23256-30-6
Apicidin	sc-202061	Apicidin is an inhibitor of HDAC3 and N-CoR. CAS # 183506-66-3	4
HC Toxin	sc-200884	HC Toxin is a potent, cell-permeable HDAC (histone deacetylase) inhibitor. HC Toxin inhibits HDACs in maize, Physarum and chicken. CAS # 83209-65-8
Artemisinin	sc-202960	Artemisinin inhibits angiogenesis by down-regulating HIF-1α and VEGF expression in mouse embryonic stem cells. Artemisinin is an inhibitor of human NOS2 (iNOS). CAS # 63968-64-9
Suramin Sodium	sc-200833	Suramin sodium uncouples G proteins from receptors presumably by blocking their interaction with intracellular receptor domains. Inhibits cell surface binding of various growth factors including PDGF, EGF and TGF-β. CAS # 129-46-4
Disulfiram	sc-205654	Disulfiram inhibits ALDH (aldehyde dehydrogenase). CAS # 97-77-8
Hymenidin	sc-202177	Antagonist of serotonergic receptors. Inhibitor of CDK5/p25 (IC₅₀=4µM) and GSK-3β (IC₅₀=12µM). CAS # 107019-95-4
DMFO Hydrochloride	sc-203563	A specific irreversible inhibitor of ornithine decarboxylase, which shows antiapoptotic, antiparasitic, and antiangiogenic activity. CAS # 70052-12-9	1